{"id":"W2028283135","doi":"10.1016/j.bbmt.2014.08.007","title":"Safety and Efficacy of Targeted-Dose Busulfan and Bortezomib as a Conditioning Regimen for Patients with Relapsed Multiple Myeloma Undergoing a Second Autologous Blood Progenitor Cell Transplantation","year":2014,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Queen Elizabeth II Health Sciences Centre","funders":"Otsuka America; Celgene; Merck; Sanofi; Novartis; Spectrum Pharmaceuticals; Amgen","keywords":"Medicine; Transplantation; Multiple myeloma; Bortezomib; Busulfan; Regimen; Pharmacokinetics; Surgery; Toxicity; Urology; Internal medicine; Hematopoietic stem cell transplantation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005990789,0.0003998177,0.0008644991,0.0002226007,0.0002773291,0.0004660875,0.0003179147,0.0003000091,0.0004503164],"category_scores_gemma":[0.0008599853,0.0001665268,0.0004296311,0.0002527738,0.0002975363,0.000310814,0.0002087632,0.000796818,0.0001642187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004786505,"about_ca_system_score_gemma":0.0006128492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002970157,"about_ca_topic_score_gemma":0.0006227891,"domain_scores_codex":[0.9996802,0.000142938,0.00002578014,0.00005371834,0.00006100848,0.00003641843],"domain_scores_gemma":[0.9995226,0.00006823747,0.0001846528,0.00003354705,0.00002016999,0.0001708797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1819052,0.01308883,0.2170814,0.0003209421,0.001227511,0.001242392,0.0004861146,0.005692651,0.1767903,0.0002634449,0.001476967,0.4004242],"study_design_scores_gemma":[0.03353043,0.5051311,0.3912369,0.000103446,0.001316186,0.005487607,0.0002522983,0.008589372,0.04773558,0.0003428002,0.006213099,0.00006109923],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986134,0.0009129382,0.0001512448,0.00003542449,0.000008706151,0.00003649323,0.00003685434,0.00001206235,0.0001930175],"genre_scores_gemma":[0.9989275,0.0002957641,0.0003152644,0.0000790653,0.00002708511,0.00004739913,0.0001946219,0.000003550168,0.0001096649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008644991,"threshold_uncertainty_score":0.003472924,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006396758255028212,"score_gpt":0.2345020117538441,"score_spread":0.2281052534988159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}