{"id":"W2028362556","doi":"10.1371/journal.pone.0032964","title":"The Colocalization Potential of HIV-Specific CD8+ and CD4+ T-Cells is Mediated by Integrin β7 but Not CCR6 and Regulated by Retinoic Acid","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Center for Research Resources; GIS-Institut des Maladies Rares; Fondation de France; Fondation du CHUM; Institut National de la Santé et de la Recherche Médicale; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"C-C chemokine receptor type 6; Biology; Cytotoxic T cell; CD8; Jurkat cells; Interleukin 21; Cell biology; CD28; T cell; Molecular biology; Immunology; Immune system; In vitro; Chemokine receptor; Chemokine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008411042,0.0001695491,0.0002367203,0.0002251652,0.0001932235,0.0005084538,0.0001530991,0.0002415117,0.002045361],"category_scores_gemma":[0.0001466596,0.0001549279,0.0001830979,0.000133209,0.0001630626,0.0002335261,0.0002616709,0.0003760766,0.0004297876],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001856285,"about_ca_system_score_gemma":0.0001081858,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004087928,"about_ca_topic_score_gemma":0.0004221258,"domain_scores_codex":[0.999814,0.00003246019,0.000009816353,0.00005187143,0.0000314227,0.00006050527],"domain_scores_gemma":[0.9999315,0.00000996517,0.00002085319,0.000009026698,0.00001192174,0.00001676806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001668005,0.00001765073,0.003877539,0.0000341986,0.00001042735,0.0001102958,0.00005789098,0.00005351835,0.9898868,0.0001528812,0.00004264333,0.005589357],"study_design_scores_gemma":[0.00003341239,0.0007036657,0.07730151,0.00002893847,0.00009856054,0.002920819,0.0004704953,0.001592776,0.9108488,0.0003919591,0.005593282,0.00001565819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99403,0.002363788,0.001839942,0.00004214236,0.000006991549,0.00001177139,0.00006837356,0.00003746186,0.001599596],"genre_scores_gemma":[0.9970018,0.0005978023,0.001242935,0.00001975134,0.000007981647,0.00001404059,0.00008773204,0.000007067646,0.001020826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002045361,"threshold_uncertainty_score":0.006842434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01601918151959755,"score_gpt":0.2076728408530131,"score_spread":0.1916536593334156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}