{"id":"W2028459965","doi":"10.1073/pnas.1409945111","title":"Activation of transcription and retrotransposition of a novel retroelement, <i>Steamer</i> , in neoplastic hemocytes of the mollusk <i>Mya arenaria</i>","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"Environment and Climate Change Canada","funders":"National Cancer Institute; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Retrotransposon; Biology; Hemolymph; Reverse transcriptase; Alu element; Transcription (linguistics); DNA; Genome; RNA; Gene; Long terminal repeat; Endogenous retrovirus; Genetics; Cell biology; Molecular biology; Virology; Human genome; Transposable element","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005494636,0.0001330191,0.00007484394,0.0001287634,0.00007274257,0.0001718468,0.0000700771,0.0001685921,0.0003445348],"category_scores_gemma":[0.00007973861,0.00008589803,0.0001441507,0.00007564456,0.0001731115,0.00007499855,0.000116751,0.0002155103,0.0001351507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001856816,"about_ca_system_score_gemma":0.00008624333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003829733,"about_ca_topic_score_gemma":0.0007222869,"domain_scores_codex":[0.9999427,0.000007424746,0.000003892974,0.00001843111,0.0000145966,0.00001304103],"domain_scores_gemma":[0.999928,0.00001153279,0.00003009202,0.00001010033,0.000006187906,0.00001418022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002143103,0.000002804646,0.0007189664,0.000004087065,0.000001284264,0.00002401971,0.0000115227,0.00001006064,0.9988351,0.00001815592,0.000004912327,0.0003475736],"study_design_scores_gemma":[0.00001293539,0.0004340349,0.1068085,0.000005664976,0.00001747005,0.0006230678,0.0001097386,0.001033737,0.8893824,0.00009251384,0.001473983,0.000005957591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998928,0.0001783985,0.0004311878,0.00001818407,0.000002733135,0.00000556253,0.0001023177,0.0000222967,0.0003113083],"genre_scores_gemma":[0.9980732,0.000100227,0.0006855539,0.00002041344,0.000003469589,0.000006999998,0.0003785977,0.000006041343,0.0007253671],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0003829733,"threshold_uncertainty_score":0.001347244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01695654380636592,"score_gpt":0.2493390744644164,"score_spread":0.2323825306580505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}