{"id":"W2028472471","doi":"10.1016/j.ydbio.2012.09.008","title":"Regulation of Drosophila mesoderm migration by phosphoinositides and the PH domain of the Rho GTP exchange factor Pebble","year":2012,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Cancer Institute; National Health and Medical Research Council; National Institutes of Health","keywords":"Pleckstrin homology domain; Cell biology; Biology; Cytokinesis; Mesoderm; RHOA; Ectoderm; Cell cortex; Guanine nucleotide exchange factor; Biochemistry; GTPase; Phosphorylation; Cytoskeleton; Embryo; Cell division; Cell; Signal transduction; Embryogenesis; Gene; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001615006,0.00008667872,0.0001137242,0.00001335746,0.0000617292,0.000002519959,0.00008011798,0.0001122143,0.00003596629],"category_scores_gemma":[0.00001019194,0.00005255006,0.00004938833,0.00004652501,0.0002458668,0.00000478068,0.00004385932,0.00003475438,6.176404e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008898851,"about_ca_system_score_gemma":0.00001868385,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006645524,"about_ca_topic_score_gemma":0.0000707233,"domain_scores_codex":[0.9994647,0.0000660673,0.0001830052,0.0001131957,0.0000553061,0.0001177201],"domain_scores_gemma":[0.9997327,0.0000129332,0.0001095074,0.00009746713,0.00002564317,0.00002178821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000840023,0.00001904404,0.08732978,0.00001205952,0.0000245206,1.590157e-8,0.0006205837,1.224741e-7,0.9111095,0.0003582635,0.00008486469,0.0003572524],"study_design_scores_gemma":[0.0005478868,0.00003187805,0.1236312,0.000006145547,0.000009938452,0.000005572736,0.0001214064,0.000004340143,0.8653185,0.0002025248,0.01005111,0.00006946731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965768,0.002018513,0.0006704767,0.0002273579,0.00009974359,0.0001864108,0.00005070334,0.000002369892,0.0001676063],"genre_scores_gemma":[0.997931,0.0002718628,0.0002081727,0.00007910181,0.00003558992,0.00001182719,0.001350524,0.000005887021,0.0001060063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.045791,"threshold_uncertainty_score":0.2142929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006819113090980147,"score_gpt":0.2001836976577516,"score_spread":0.1933645845667714,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}