{"id":"W2028491723","doi":"10.1038/sj.embor.embor869","title":"Getting a grip on non‐native proteins","year":2003,"lang":"en","type":"review","venue":"EMBO Reports","topic":"Heat shock proteins research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"ca_institutions":"Simon Fraser University","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Native state; Protein folding; Protein aggregation; Co-chaperone; Function (biology); Membrane protein; Biology; Cell biology; Chemistry; Biochemistry; Membrane; Heat shock protein; Gene; Hsp90","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001524264,0.001972379,0.002965793,0.001893027,0.0008743736,0.002205158,0.002373601,0.002945285,0.00366264],"category_scores_gemma":[0.001302037,0.0007576615,0.0005866401,0.002803977,0.002801561,0.005418475,0.001645705,0.00436873,0.00780395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00134494,"about_ca_system_score_gemma":0.001017686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008398448,"about_ca_topic_score_gemma":0.001521122,"domain_scores_codex":[0.9996094,0.00004678564,0.00005827567,0.00006520661,0.0001712621,0.00004911077],"domain_scores_gemma":[0.9993186,0.0003043043,0.00006521233,0.00005800503,0.0001852869,0.00006870279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001935319,0.0001176962,0.0001068516,0.01274107,0.00009600537,0.0004725144,0.0001565284,0.0004073721,0.01546906,0.01324981,0.09759036,0.8593991],"study_design_scores_gemma":[0.00001506301,0.00003115672,0.0001213293,0.0004712843,0.00002514388,0.0005328975,0.0000413785,0.00003595873,0.002669437,0.002790122,0.9932523,0.00001380564],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001335994,0.9951462,0.0008901561,0.0007309773,0.001750139,0.000007189555,0.00001535841,0.00003035148,0.001295938],"genre_scores_gemma":[0.0006346111,0.9938626,0.0007461967,0.0008357879,0.0007679194,0.00001645628,0.00004741047,0.00001168809,0.003077325],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00366264,"threshold_uncertainty_score":0.01225275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03904719394908176,"score_gpt":0.3640217083137026,"score_spread":0.3249745143646209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}