{"id":"W2028506756","doi":"10.1074/jbc.m109.082115","title":"Cooperative Regulation of the Induction of the Novel Antibacterial Listericin by Peptidoglycan Recognition Protein LE and the JAK-STAT Pathway","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Japan Science and Technology Agency; National Institutes of Health; Japan Society for the Promotion of Science; Centre National de la Recherche Scientifique; Deutsches Krebsforschungszentrum; Institute of Genetics; Naito Foundation","keywords":"Biology; Listeria monocytogenes; Intracellular parasite; Microbiology; Intracellular; Pattern recognition receptor; Peptidoglycan; Innate immune system; Cell biology; Immune system; Gene; Bacteria; Biochemistry; Immunology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006522712,0.0001056114,0.0002448292,0.00001076615,0.0001416011,0.000009843699,0.0002373606,0.0003014541,0.0001127081],"category_scores_gemma":[0.0005166163,0.00004344567,0.0001111484,0.00009239182,0.000862109,0.00005245091,0.00009252223,0.0005377734,7.886082e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001407674,"about_ca_system_score_gemma":0.0001016666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002037262,"about_ca_topic_score_gemma":0.00000219732,"domain_scores_codex":[0.999,0.000322757,0.0004260134,0.00009881172,0.00004914476,0.0001033066],"domain_scores_gemma":[0.9987305,0.000103508,0.0007827532,0.0001611202,0.0002123498,0.000009743044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001158752,0.00008786806,0.00004314669,0.00001126455,0.00004391357,1.121139e-7,0.0001465291,4.363778e-7,0.9975209,0.00009253841,0.0000693469,0.0008251653],"study_design_scores_gemma":[0.001793249,0.0001334465,0.002332778,0.00006230704,0.00001853977,0.000194119,0.0002606698,0.000003654749,0.9942844,0.0003129753,0.000547345,0.00005651576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998412,0.0001015743,0.00006331231,0.0006873807,0.0003856342,0.0002088396,0.00004863202,0.000002979981,0.00008965993],"genre_scores_gemma":[0.9995031,0.00001470585,0.00005458246,0.0000382565,0.00005539219,0.000004075354,0.00001373856,0.000004549892,0.0003115704],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003236526,"threshold_uncertainty_score":0.3176476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01472664276584808,"score_gpt":0.202807242845664,"score_spread":0.1880806000798159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}