{"id":"W2028506756","doi":"10.1074/jbc.m109.082115","title":"Cooperative Regulation of the Induction of the Novel Antibacterial Listericin by Peptidoglycan Recognition Protein LE and the JAK-STAT Pathway","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Japan Science and Technology Agency; National Institutes of Health; Japan Society for the Promotion of Science; Centre National de la Recherche Scientifique; Deutsches Krebsforschungszentrum; Institute of Genetics; Naito Foundation","keywords":"Biology; Listeria monocytogenes; Intracellular parasite; Microbiology; Intracellular; Pattern recognition receptor; Peptidoglycan; Innate immune system; Cell biology; Immune system; Gene; Bacteria; Biochemistry; Immunology; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001391683,0.0002545376,0.0001553776,0.0001598735,0.0001052071,0.000318567,0.00008635459,0.0001167298,0.0007470609],"category_scores_gemma":[0.00009358182,0.0001102394,0.0001675914,0.00007344432,0.0002029672,0.0001710989,0.0002453257,0.0002852837,0.0002653209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002012235,"about_ca_system_score_gemma":0.0001498733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009493056,"about_ca_topic_score_gemma":0.0002055579,"domain_scores_codex":[0.9998739,0.00002489756,0.000008905209,0.00002723432,0.00002781606,0.00003725339],"domain_scores_gemma":[0.9999046,0.00001942685,0.00002781728,0.00000788806,0.00001115633,0.00002906374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009777163,0.00001097647,0.0004024485,0.00002052638,0.000002666329,0.00006724559,0.000007896744,0.00006010108,0.9984655,0.0001008118,0.00002005553,0.0007441227],"study_design_scores_gemma":[0.00004192315,0.0003038523,0.0355426,0.00001126176,0.00003047229,0.0004996256,0.00007523215,0.00449111,0.9566545,0.0002599476,0.002080602,0.000008849222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936435,0.001536812,0.002760369,0.00008803234,0.0000184658,0.00001099936,0.000178603,0.00007271487,0.001690421],"genre_scores_gemma":[0.9973258,0.0003079644,0.001051667,0.00003502064,0.000007510614,0.000007910526,0.0002381133,0.000007059452,0.001018957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007470609,"threshold_uncertainty_score":0.002499163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01472664276584808,"score_gpt":0.202807242845664,"score_spread":0.1880806000798159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}