{"id":"W2028540870","doi":"10.1007/s10637-009-9332-7","title":"Chemopreventive doses of resveratrol do not produce cardiotoxicity in a rodent model of hepatocellular carcinoma","year":2009,"lang":"en","type":"article","venue":"Investigational New Drugs","topic":"Sirtuins and Resveratrol in Medicine","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"BioPhage Pharma (Canada)","funders":"Louisiana Board of Regents; Ohio Board of Regents","keywords":"Resveratrol; Cardiotoxicity; Medicine; Pharmacology; Hepatocellular carcinoma; Carcinogen; Liver cancer; Carcinogenesis; Cancer; Internal medicine; Toxicity; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004353887,0.0001969196,0.0006020748,0.0002301471,0.00002885244,0.000005727134,0.0001390219,0.0001199377,0.0000284592],"category_scores_gemma":[0.0003080855,0.0001662346,0.0001675092,0.0003725442,0.0002147083,0.00008904312,0.00003065257,0.0002636884,0.00000240145],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009945027,"about_ca_system_score_gemma":0.0008794286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002936477,"about_ca_topic_score_gemma":0.00000361651,"domain_scores_codex":[0.9978641,0.00005770695,0.000663102,0.0003593027,0.0008355362,0.0002202111],"domain_scores_gemma":[0.9988518,0.0000642404,0.0002223808,0.0003667706,0.0002689667,0.0002258894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006309526,0.0004301392,0.1499847,0.0002162471,0.00008676434,0.00003989985,0.003207991,0.007231058,0.8314653,0.003265994,0.002081887,0.001359031],"study_design_scores_gemma":[0.00461828,0.0004817365,0.165204,0.0006498733,0.0001527958,0.0000314161,0.0002105122,0.04537527,0.774035,0.00893294,0.00008369201,0.0002244625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929057,0.0008219368,0.0001880413,0.004468052,0.00006517365,0.0006321397,0.0000212024,0.00001641588,0.0008812891],"genre_scores_gemma":[0.9938976,0.00004088751,0.004121657,0.0009337399,0.0002780507,0.00001175861,0.00003647454,0.00001468182,0.0006652146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05743025,"threshold_uncertainty_score":0.6778852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0273199683245389,"score_gpt":0.2657664345778118,"score_spread":0.2384464662532729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}