{"id":"W2028657027","doi":"10.1007/s00775-008-0431-2","title":"Intraprotein electron transfer in inducible nitric oxide synthase holoenzyme","year":2008,"lang":"en","type":"article","venue":"JBIC Journal of Biological Inorganic Chemistry","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"National Heart, Lung, and Blood Institute; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Flavin mononucleotide; Heme; Flash photolysis; Nitric oxide synthase; Electron transfer; ATP synthase; Photochemistry; Kinetics; Reaction rate constant; Enzyme; Stereochemistry; Flavin group; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004964261,0.0002264968,0.0006449869,0.0001262062,0.00004531906,0.000007085803,0.0002115405,0.0003811585,0.000543176],"category_scores_gemma":[0.0006865928,0.0001558431,0.0002170183,0.0006079735,0.0001404419,0.00006931776,0.00002731015,0.001170876,0.00002527667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001970725,"about_ca_system_score_gemma":0.0002858397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001466564,"about_ca_topic_score_gemma":4.038574e-7,"domain_scores_codex":[0.9982657,0.00007077598,0.0007053094,0.0002491136,0.000272863,0.0004362265],"domain_scores_gemma":[0.999097,0.0001847189,0.0001334466,0.0002152606,0.0001077524,0.0002617493],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005198013,0.0004813072,0.01636487,0.00005648012,0.00005224059,0.001626258,0.00003354366,0.000001528711,0.9802197,0.000003913883,0.0002498516,0.0003905669],"study_design_scores_gemma":[0.002809733,0.0004821209,0.02910143,0.0001225311,0.00004379189,0.007324044,0.00006222931,0.000004481003,0.9593731,0.0001126689,0.0003886376,0.0001752121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968171,0.002016544,0.00009142549,0.0003620317,0.00003549103,0.0001592476,0.000002572573,0.0000278407,0.0004877207],"genre_scores_gemma":[0.9978272,0.001067177,0.0002170699,0.0003229779,0.0003556194,0.000005139796,0.000005012215,0.0000186153,0.0001811528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02084652,"threshold_uncertainty_score":0.6355097,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0262341552355098,"score_gpt":0.2582556266618547,"score_spread":0.2320214714263449,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}