{"id":"W2028662696","doi":"10.1158/0008-5472.can-10-3590","title":"Interaction between <i>MYC</i> and <i>MCL1</i> in the Genesis and Outcome of Non–Small-Cell Lung Cancer","year":2011,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"National Cancer Institute","keywords":"MCL1; KRAS; Carcinogenesis; Cancer research; Lung cancer; Adenocarcinoma; Apoptosis; Cancer; Medicine; Lung; Biology; Cell; Oncology; Internal medicine; Gene; Downregulation and upregulation; Colorectal cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003753427,0.0002662501,0.0002265015,0.0002612725,0.0001613575,0.000375415,0.0001794578,0.000287378,0.001024852],"category_scores_gemma":[0.000196129,0.0001509961,0.0002387645,0.00009691521,0.000329207,0.0001910358,0.0002090511,0.0005405624,0.0002571797],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003035285,"about_ca_system_score_gemma":0.0001594924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002927417,"about_ca_topic_score_gemma":0.0005272527,"domain_scores_codex":[0.9997037,0.0000971281,0.00001956913,0.00003993039,0.00006219382,0.00007745973],"domain_scores_gemma":[0.9998022,0.00004822965,0.00005357861,0.00002201056,0.00001158068,0.00006236776],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004179529,0.00006734407,0.001234058,0.00002679125,0.00001144816,0.000100093,0.000009016313,0.00007965277,0.9963011,0.0002137991,0.00005102228,0.001487759],"study_design_scores_gemma":[0.00005584615,0.001181231,0.02225425,0.000009367488,0.00004417351,0.001153541,0.00003546654,0.001444662,0.9713788,0.0001166295,0.002318132,0.000007955619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957216,0.002079116,0.0009711424,0.0001780839,0.00001606882,0.000009371379,0.00006438014,0.00004569836,0.0009145674],"genre_scores_gemma":[0.998656,0.000395348,0.0003405257,0.00004219688,0.000006392698,0.000008879531,0.00006861979,0.000005286326,0.0004766547],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001024852,"threshold_uncertainty_score":0.003428459,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07862494546113312,"score_gpt":0.3791732443580748,"score_spread":0.3005482988969417,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}