{"id":"W2028680775","doi":"10.1089/dna.2006.25.104","title":"Cloning and Functional Characterization of the Murine Caspase-3 Gene Promoter","year":2006,"lang":"en","type":"article","venue":"DNA and Cell Biology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique; Armand Frappier Museum; Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Medical Research Council Canada; Canada Research Chairs; Alzheimer Society","keywords":"Biology; Promoter; Molecular biology; Jurkat cells; Gene; Transcription factor; Untranslated region; Reporter gene; Regulation of gene expression; Luciferase; Gene expression; Caspase; Genetics; Cell biology; Transfection; Programmed cell death; Apoptosis; T cell; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004827565,0.0004668954,0.0003201615,0.0005383444,0.0002907615,0.0003637373,0.0005035755,0.0003301603,0.001950559],"category_scores_gemma":[0.0005240496,0.0003042987,0.0007461677,0.0003609803,0.0003704539,0.0003028888,0.0003022057,0.001550436,0.001490631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006527631,"about_ca_system_score_gemma":0.0007153667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001099104,"about_ca_topic_score_gemma":0.001268712,"domain_scores_codex":[0.9997051,0.00004568322,0.00003435745,0.00006772062,0.00007204423,0.0000750521],"domain_scores_gemma":[0.999567,0.0001203954,0.00008492295,0.00005464465,0.00008519753,0.00008788013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001000537,0.00005612045,0.000197619,0.00006237339,0.000004027711,0.00006056661,0.00003921715,0.0002138895,0.9957409,0.0004289678,0.00005686592,0.003039457],"study_design_scores_gemma":[0.00007981644,0.0004130117,0.00374961,0.00005208626,0.00003448254,0.0004715154,0.00004177162,0.002504877,0.9777825,0.0003997789,0.01445162,0.00001888347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8331084,0.004420436,0.1468419,0.0006637964,0.0001823292,0.001071936,0.008670084,0.0004385738,0.004602436],"genre_scores_gemma":[0.7882552,0.003167234,0.1747361,0.0002160662,0.0000841173,0.0005929411,0.02356327,0.0002599058,0.009125259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001950559,"threshold_uncertainty_score":0.006525278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003999916990653213,"score_gpt":0.172074435512061,"score_spread":0.1680745185214078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}