{"id":"W2028680775","doi":"10.1089/dna.2006.25.104","title":"Cloning and Functional Characterization of the Murine Caspase-3 Gene Promoter","year":2006,"lang":"en","type":"article","venue":"DNA and Cell Biology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique; Armand Frappier Museum; Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Medical Research Council Canada; Canada Research Chairs; Alzheimer Society","keywords":"Biology; Promoter; Molecular biology; Jurkat cells; Gene; Transcription factor; Untranslated region; Reporter gene; Regulation of gene expression; Luciferase; Gene expression; Caspase; Genetics; Cell biology; Transfection; Programmed cell death; Apoptosis; T cell; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004274302,0.00005582903,0.00005551869,0.00001251061,0.00005334026,0.000003831761,0.00002026732,0.00008803307,0.00001036134],"category_scores_gemma":[0.000001792446,0.00003763168,0.00001987756,0.00002198701,0.00005423449,0.000001313404,0.00004385119,0.00002182158,2.867274e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000144016,"about_ca_system_score_gemma":0.000007939865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001569179,"about_ca_topic_score_gemma":0.000007067742,"domain_scores_codex":[0.9996682,0.00002253453,0.00008764026,0.0001324131,0.00002032247,0.00006883898],"domain_scores_gemma":[0.9998373,0.000002344186,0.00005186598,0.00007559769,0.00002047943,0.00001239071],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001332532,0.00001487812,0.002524521,0.00000810764,0.000003879932,1.335672e-7,0.00000680215,0.000002906266,0.9959251,0.0002901586,0.00001075145,0.001199433],"study_design_scores_gemma":[0.0002141454,0.00007532649,0.07131678,0.000002001995,0.000008359756,0.000009494166,0.000003072161,0.00007548316,0.9213457,0.0001859076,0.006715311,0.00004843541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982029,0.0002714112,0.001024611,0.00006499732,0.0001132877,0.0000766357,0.00001153444,0.000002335171,0.000232353],"genre_scores_gemma":[0.9984707,0.0001113351,0.00007265889,0.00004535925,0.0001523896,0.000003814303,0.0003068372,0.000004492285,0.0008324402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07457942,"threshold_uncertainty_score":0.1534575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003999916990653213,"score_gpt":0.172074435512061,"score_spread":0.1680745185214078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}