{"id":"W2028702634","doi":"10.1089/107999001750277853","title":"The Interferon-Inducible Stat2:Stat1 Heterodimer Preferentially Binds <i>In Vitro</i> to a Consensus Element Found in the Promoters of a Subset of Interferon-Stimulated Genes","year":2001,"lang":"en","type":"article","venue":"Journal of Interferon & Cytokine Research","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"STAT2; STAT1; Enhancer; Response element; STAT protein; Promoter; STAT4; Biology; Interferon; Transcription factor; Molecular biology; Gene; Consensus sequence; Transcription (linguistics); STAT3; Gene expression; Genetics; stat; Peptide sequence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005664896,0.0003583036,0.0009421681,0.001587895,0.0001228617,0.0001121746,0.0009359082,0.0001407768,0.0001747681],"category_scores_gemma":[0.0007479294,0.0002133416,0.0003388301,0.001553451,0.0003511583,0.0001572602,0.0002981776,0.001808598,0.0000131173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006296833,"about_ca_system_score_gemma":0.0007967943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008166054,"about_ca_topic_score_gemma":0.001020247,"domain_scores_codex":[0.9937029,0.001038006,0.002425832,0.0004163895,0.001533731,0.0008831162],"domain_scores_gemma":[0.9951577,0.001133701,0.0006676326,0.0007897553,0.002007016,0.0002441759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.03036511,0.001520155,0.001851786,0.0001729988,0.0003791318,0.0002124079,0.003748627,0.0007467833,0.9527889,0.00003044739,0.00239413,0.005789507],"study_design_scores_gemma":[0.007797023,0.02997431,0.003639913,0.003964145,0.0001550416,0.001020778,0.007968254,0.002114241,0.9319114,0.0001175813,0.01098027,0.0003570186],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992189,0.0005300862,0.0003496799,0.004864345,0.0003436329,0.001202413,0.00004799586,0.00000857107,0.0004642519],"genre_scores_gemma":[0.9988363,0.0003047058,0.0002421139,0.0001158332,0.0001795491,0.00004629309,0.0000145858,0.00005259118,0.0002080342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02845416,"threshold_uncertainty_score":0.8699818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1172768751942882,"score_gpt":0.4110993538255547,"score_spread":0.2938224786312665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}