{"id":"W2028702634","doi":"10.1089/107999001750277853","title":"The Interferon-Inducible Stat2:Stat1 Heterodimer Preferentially Binds <i>In Vitro</i> to a Consensus Element Found in the Promoters of a Subset of Interferon-Stimulated Genes","year":2001,"lang":"en","type":"article","venue":"Journal of Interferon & Cytokine Research","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"STAT2; STAT1; Enhancer; Response element; STAT protein; Promoter; STAT4; Biology; Interferon; Transcription factor; Molecular biology; Gene; Consensus sequence; Transcription (linguistics); STAT3; Gene expression; Genetics; stat; Peptide sequence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002340539,0.0004586455,0.0002425777,0.0002096125,0.0001985761,0.0003833788,0.0002020753,0.0002147616,0.003598674],"category_scores_gemma":[0.0001244582,0.0002181384,0.0002964796,0.0001767305,0.0001539442,0.0001598651,0.0002194113,0.0004882374,0.001421255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002693487,"about_ca_system_score_gemma":0.0001921047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002632993,"about_ca_topic_score_gemma":0.0005429348,"domain_scores_codex":[0.999675,0.00005728246,0.00002143157,0.00008221972,0.00009181935,0.00007228403],"domain_scores_gemma":[0.9999009,0.0000198556,0.00002374719,0.00001008814,0.0000133867,0.00003207025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007254292,0.00001695324,0.0005713803,0.00002461311,0.0000068949,0.00002579333,0.000007476511,0.00003196304,0.9985334,0.00005184889,0.00008605965,0.0005710761],"study_design_scores_gemma":[0.0000395011,0.0002209075,0.01932933,0.00001937805,0.00003534662,0.000748923,0.00007210503,0.002060373,0.9703249,0.0001031909,0.00703737,0.000008812233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816223,0.003996297,0.008762192,0.0002205482,0.0001209691,0.00004172701,0.0009747902,0.0001558246,0.004105289],"genre_scores_gemma":[0.9886341,0.0007253295,0.002890598,0.0001883295,0.00003863269,0.00004227276,0.003796412,0.00004340957,0.003640901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003598674,"threshold_uncertainty_score":0.01203871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1172768751942882,"score_gpt":0.4110993538255547,"score_spread":0.2938224786312665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}