{"id":"W2028723798","doi":"10.1002/jps.22249","title":"Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Mefloquine Hydrochloride","year":2010,"lang":"en","type":"review","venue":"Journal of Pharmaceutical Sciences","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Rijksinstituut voor Volksgezondheid en Milieu","keywords":"Bioequivalence; Biopharmaceutics Classification System; Pharmacology; Active ingredient; Dosage form; Bioavailability; Excipient; Drug; Mefloquine; Medicine; Chemistry; Malaria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004195033,0.00137837,0.0009749904,0.003362086,0.0002927213,0.0005557455,0.0007333205,0.001134884,0.01785527],"category_scores_gemma":[0.0005174495,0.00030003,0.0003177701,0.001665393,0.0003432903,0.000956631,0.000619463,0.001328976,0.01424203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002482391,"about_ca_system_score_gemma":0.0006818398,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00100237,"about_ca_topic_score_gemma":0.002626999,"domain_scores_codex":[0.999752,0.00003211125,0.00003961155,0.00002635426,0.0001322641,0.00001763701],"domain_scores_gemma":[0.999648,0.0000989935,0.0001051095,0.00001430869,0.0001082585,0.00002544959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007683118,0.0001033437,0.00005523123,0.004057509,0.0000134724,0.0001703134,0.00003625999,0.0001559103,0.01781935,0.0009176509,0.05700747,0.9195867],"study_design_scores_gemma":[0.00002438821,0.0001523316,0.0006194597,0.0006594743,0.00003045841,0.0009459145,0.00001822475,0.0001170672,0.004822067,0.0002932946,0.9923065,0.00001068511],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003202499,0.9397619,0.007680689,0.001627823,0.002980446,0.0002547254,0.000705725,0.000478483,0.04330766],"genre_scores_gemma":[0.01093083,0.8029619,0.006813955,0.001742119,0.001798635,0.0002514944,0.001329621,0.0001032875,0.1740682],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01785527,"threshold_uncertainty_score":0.05973178,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2792105498216242,"score_gpt":0.5387694900199056,"score_spread":0.2595589401982814,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}