{"id":"W2028753869","doi":"10.1021/la0628930","title":"Molecular Recognition Forces between Immunoglobulin G and a Surface Protein Adhesin on Living <i>Staphylococcus aureus</i>","year":2007,"lang":"en","type":"article","venue":"Langmuir","topic":"Biochemical and Structural Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Bacterial adhesin; Staphylococcus aureus; Protein A; Linker; Chemistry; Immunoglobulin G; Molecule; Fragment crystallizable region; Biophysics; Bacteria; Microbiology; Nanotechnology; Antibody; Virulence; Materials science; Biochemistry; Receptor; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001009988,0.0001486323,0.000112237,0.0001185884,0.0002186292,0.0001715702,0.0001871357,0.0002425541,0.00085119],"category_scores_gemma":[0.0002612073,0.00008178999,0.0001076019,0.00007199895,0.0002437287,0.000139264,0.0001405597,0.0002718714,0.0001460507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000240045,"about_ca_system_score_gemma":0.00009730804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001173026,"about_ca_topic_score_gemma":0.0009683375,"domain_scores_codex":[0.999894,0.00001411577,0.000002985561,0.00001848052,0.00004395165,0.00002644252],"domain_scores_gemma":[0.9998442,0.00007639249,0.00002896947,0.00000613466,0.0000187878,0.00002540145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003786766,0.00001333353,0.0005346296,0.00001547717,0.000004004919,0.00005766326,0.00002693239,0.00009370478,0.9982723,0.0000582111,0.00003318394,0.0008526513],"study_design_scores_gemma":[0.00001397928,0.0003667804,0.01470652,0.000004802198,0.00001678067,0.0002941649,0.0001255255,0.00429686,0.9792997,0.0001062012,0.0007572375,0.00001127187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990042,0.0001763718,0.0004738331,0.00002303187,0.000004606084,0.000001588078,0.00001315901,0.000007248827,0.0002959316],"genre_scores_gemma":[0.9983435,0.0001402683,0.001075306,0.00002369776,0.000008308106,0.000003874986,0.00004634831,0.00000314717,0.00035544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001173026,"threshold_uncertainty_score":0.002847493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00847840646342566,"score_gpt":0.2244349615069591,"score_spread":0.2159565550435334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}