{"id":"W2028778894","doi":"10.1016/j.molimm.2009.11.006","title":"Junctional diversity prevents negative selection of an antigen-specific T cell repertoire","year":2009,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Superantigen; Antigen; T-cell receptor; Negative selection; Molecular biology; Repertoire; T cell; Gene; Cell biology; Genetics; Immune system; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003803449,0.0002852603,0.000419817,0.0003461785,0.0003280315,0.0006263327,0.0006498716,0.0005462249,0.003188187],"category_scores_gemma":[0.0005345367,0.0003426078,0.0001689151,0.0001420873,0.0004345829,0.0002722808,0.0006706067,0.001586618,0.0008177182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002371785,"about_ca_system_score_gemma":0.0002344197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000153874,"about_ca_topic_score_gemma":0.0003723172,"domain_scores_codex":[0.9993395,0.0001300417,0.00003598867,0.00008985613,0.0001941744,0.0002104036],"domain_scores_gemma":[0.9991912,0.0002642194,0.0001237938,0.0001531968,0.00005101718,0.0002165642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009202372,0.0000259476,0.0001054846,0.000009938835,0.000003519098,0.00003612785,0.000006806587,0.00005001558,0.9987482,0.0002750955,0.0000332879,0.0006135119],"study_design_scores_gemma":[0.00004841296,0.0003251451,0.003527996,0.0000115847,0.00003447215,0.001021173,0.0000365993,0.001874483,0.9898263,0.0004478227,0.002835749,0.00001020073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994818,0.0004024752,0.001642895,0.00007760279,0.00005480844,0.000018219,0.00006099338,0.00008414454,0.002840832],"genre_scores_gemma":[0.9980002,0.0001201885,0.0005330749,0.00008626655,0.00002387933,0.000008493037,0.00008114503,0.00004178382,0.00110483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003188187,"threshold_uncertainty_score":0.0106656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007876623369860005,"score_gpt":0.2022677915217367,"score_spread":0.1943911681518767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}