{"id":"W2028778894","doi":"10.1016/j.molimm.2009.11.006","title":"Junctional diversity prevents negative selection of an antigen-specific T cell repertoire","year":2009,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Superantigen; Antigen; T-cell receptor; Negative selection; Molecular biology; Repertoire; T cell; Gene; Cell biology; Genetics; Immune system; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001887643,0.0003174483,0.0004862133,0.0002692182,0.0005339058,0.000009283653,0.0005033685,0.0006325429,0.0009635958],"category_scores_gemma":[0.00002833984,0.0003216934,0.0002058464,0.0003245554,0.0004790682,0.0001733903,0.0002543624,0.000560394,0.0002769484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008613642,"about_ca_system_score_gemma":0.00007540847,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001560914,"about_ca_topic_score_gemma":0.000009476597,"domain_scores_codex":[0.997721,0.0005906776,0.0004558367,0.0006058124,0.00007325492,0.0005534831],"domain_scores_gemma":[0.9989257,0.00005502483,0.0002975472,0.0005061431,0.000187885,0.0000276546],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006040666,0.0009075939,0.0007422662,0.000004442271,0.0002456887,0.00002727819,0.0003566634,0.00002028723,0.9881889,0.001026214,0.0005141579,0.007362507],"study_design_scores_gemma":[0.002340398,0.001708551,0.01503632,0.00001233412,0.00003551731,0.0002094947,0.0001793183,0.000004961961,0.9673104,0.001448745,0.01141019,0.0003037874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910419,0.004524044,0.0009143979,0.0001699303,0.0009356017,0.0002932536,0.00001657071,0.0001285053,0.001975792],"genre_scores_gemma":[0.9971289,0.0004167588,0.0004459858,0.0002105989,0.00002237965,0.000008240117,0.0001831221,0.00001983971,0.001564164],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02087845,"threshold_uncertainty_score":0.9999496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007876623369860005,"score_gpt":0.2022677915217367,"score_spread":0.1943911681518767,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}