{"id":"W2028829776","doi":"10.1016/j.bone.2010.01.098","title":"Results From a Phase 3 Randomized, Double-Blind, Double-Dummy Clinical Trial Comparing Denosumab with Zoledronic Acid for the Management of Bone Metastases in Patients with Advanced Solid Tumors or Multiple Myeloma","year":2010,"lang":"en","type":"article","venue":"Bone","topic":"Bone health and treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Denosumab; Zoledronic acid; Medicine; Multiple myeloma; Double blind; Oncology; Randomized controlled trial; Internal medicine; Pathology; Osteoporosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002923672,0.001846981,0.005076712,0.0004998058,0.0006429937,0.00118447,0.00119579,0.002625839,0.007776613],"category_scores_gemma":[0.003605182,0.0008210317,0.00320734,0.000561677,0.001702992,0.001253351,0.0004479041,0.003613259,0.001074803],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007669459,"about_ca_system_score_gemma":0.001535163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001284911,"about_ca_topic_score_gemma":0.002646388,"domain_scores_codex":[0.9987234,0.0007314983,0.000109806,0.0001830215,0.00008973473,0.0001625119],"domain_scores_gemma":[0.9977645,0.0009833818,0.0004281563,0.0001888755,0.0001320376,0.0005030812],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9897494,0.002758496,0.0001196053,0.0003523721,0.0007531367,0.00001326899,0.00002143531,0.0001383208,0.001322522,0.00004622028,0.0002758653,0.00444944],"study_design_scores_gemma":[0.9830803,0.01579283,0.0003900701,0.00001002419,0.0003389182,0.000008239671,0.00000559949,0.00007414637,0.0001280746,0.0000546017,0.0001115904,0.000005694715],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9743817,0.009824785,0.001547381,0.001457425,0.001068709,0.006604099,0.002396939,0.0001983398,0.002520567],"genre_scores_gemma":[0.9806943,0.004430054,0.002766617,0.002205025,0.0007459763,0.004659043,0.002059577,0.00005426889,0.002385181],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007776613,"threshold_uncertainty_score":0.0260154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0754410233069911,"score_gpt":0.385467380485443,"score_spread":0.3100263571784519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}