{"id":"W2028829776","doi":"10.1016/j.bone.2010.01.098","title":"Results From a Phase 3 Randomized, Double-Blind, Double-Dummy Clinical Trial Comparing Denosumab with Zoledronic Acid for the Management of Bone Metastases in Patients with Advanced Solid Tumors or Multiple Myeloma","year":2010,"lang":"en","type":"article","venue":"Bone","topic":"Bone health and treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Denosumab; Zoledronic acid; Medicine; Multiple myeloma; Double blind; Oncology; Randomized controlled trial; Internal medicine; Pathology; Osteoporosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001226489,0.000358084,0.001827234,0.0001461274,0.000135531,0.00002325671,0.0001413882,0.0001088628,0.00002738941],"category_scores_gemma":[0.0001418132,0.0001840172,0.0002164991,0.0002756531,0.0002612892,0.0001327593,0.0000698798,0.0004114302,0.000008733783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000620045,"about_ca_system_score_gemma":0.0002562397,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005836226,"about_ca_topic_score_gemma":0.003129269,"domain_scores_codex":[0.9965097,0.00009840978,0.001718504,0.0005965442,0.0005300032,0.0005468533],"domain_scores_gemma":[0.9970279,0.0009138478,0.000842165,0.0007667965,0.0001747123,0.000274616],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.973899,0.005279344,0.003812599,0.0001346006,0.001157695,0.0001363808,0.0001434911,0.00003054236,0.00001512975,0.00003953882,0.00003083837,0.01532082],"study_design_scores_gemma":[0.9839282,0.004824694,0.006922103,0.0004683658,0.001656588,0.000009882012,0.0001235721,0.0005459231,0.0008756103,0.0000097345,0.0004269196,0.0002084061],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9860612,0.0002647053,0.000316655,0.0002142062,0.0003061503,0.01249211,0.0002116073,0.00004188876,0.0000915007],"genre_scores_gemma":[0.9861567,0.0000553317,0.01129767,0.0000745938,0.00009306844,0.001486867,0.0006244037,0.00005303256,0.0001583279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01511241,"threshold_uncertainty_score":0.7504003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0754410233069911,"score_gpt":0.385467380485443,"score_spread":0.3100263571784519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}