{"id":"W2028897202","doi":"10.1038/nrc2981","title":"Regulation of cancer cell metabolism","year":2011,"lang":"en","type":"review","venue":"Nature reviews. Cancer","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4759,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Warburg effect; Carcinogenesis; Biology; Cancer; Cancer cell; Oncogene; Metabolism; Metabolic pathway; Tumor microenvironment; Cell metabolism; Cell; Cancer research; Genetics; Cell cycle; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005533426,0.001547969,0.001874455,0.001503231,0.0004259114,0.001585289,0.001541628,0.001807589,0.003657472],"category_scores_gemma":[0.0003994396,0.0004834318,0.0004723555,0.002248809,0.001064126,0.001405769,0.001388798,0.002531513,0.003879883],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001255226,"about_ca_system_score_gemma":0.001169438,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008579837,"about_ca_topic_score_gemma":0.001847907,"domain_scores_codex":[0.9997184,0.00004240896,0.00002583942,0.00004522684,0.0001250482,0.00004314266],"domain_scores_gemma":[0.9997619,0.00005190486,0.00004086036,0.00001390416,0.000080783,0.00005063667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000111519,0.00005785922,0.0001632172,0.007476488,0.00006105507,0.0002340567,0.00004250437,0.0005510367,0.01251884,0.01097584,0.09902295,0.8687845],"study_design_scores_gemma":[0.00002042993,0.00003967693,0.0006583527,0.0009083084,0.00004102759,0.0007304183,0.00003146226,0.0001492866,0.001513353,0.0043162,0.9915731,0.00001831348],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000105002,0.9966247,0.0004101153,0.0006820965,0.0006473465,0.000005261876,0.00003204162,0.00001992599,0.001473502],"genre_scores_gemma":[0.0008668354,0.9971884,0.0001848089,0.0003070253,0.0003759579,0.000008524812,0.00006143925,0.000002159422,0.001004818],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003657472,"threshold_uncertainty_score":0.0122354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02680419724454376,"score_gpt":0.345882358406347,"score_spread":0.3190781611618033,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}