{"id":"W2028902554","doi":"10.1016/j.ymgme.2012.06.001","title":"Left ventricular aneurysm in an adult patient with mucopolysaccharidosis type I: Comment on pathogenesis of a novel complication","year":2012,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"","keywords":"Mucopolysaccharidosis type I; Pathogenesis; Enzyme replacement therapy; Medicine; Mucopolysaccharidosis; Glycosaminoglycan; Cardiomyopathy; Extracellular matrix; Complication; Aneurysm; Mucopolysaccharidosis I; Hurler syndrome; Dermatan sulfate; Heparan sulfate; Lysosomal storage disease; Pathology; Cardiology; Disease; Internal medicine; Heart failure; Surgery; Anatomy; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001268181,0.00197168,0.001697481,0.001680038,0.001459867,0.001826907,0.002972453,0.02481817,0.001867919],"category_scores_gemma":[0.008376123,0.0008366502,0.001989231,0.0006791329,0.002987916,0.003387312,0.00117344,0.007861946,0.0009772372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001241213,"about_ca_system_score_gemma":0.0005436692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004983544,"about_ca_topic_score_gemma":0.0006968513,"domain_scores_codex":[0.9989355,0.0002041606,0.0001791338,0.0002767569,0.0001598912,0.0002445221],"domain_scores_gemma":[0.9947187,0.003320464,0.0007262675,0.0003765947,0.0002089316,0.0006490519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00008582487,0.00001558181,0.004093833,0.00006608967,0.00002410938,0.9876848,0.0001008686,0.0001004998,0.0006723257,0.001605129,0.004139213,0.001411594],"study_design_scores_gemma":[0.00007460772,0.0001321758,0.005159734,0.00009496536,0.00007314159,0.9830262,0.0001622289,0.0008835843,0.0009195857,0.002520382,0.006904695,0.00004866517],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4340336,0.05861962,0.02593133,0.3586252,0.06073784,0.0004122257,0.0009626021,0.001625332,0.05905211],"genre_scores_gemma":[0.7867958,0.007988704,0.00555577,0.05216557,0.1418868,0.0001456529,0.0002455752,0.0001443983,0.00507187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02481817,"threshold_uncertainty_score":0.009005606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02026309910677896,"score_gpt":0.2778753129733082,"score_spread":0.2576122138665292,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}