{"id":"W2028913886","doi":"10.1038/cgt.2012.63","title":"Neural stem cell-based dual suicide gene delivery for metastatic brain tumors","year":2012,"lang":"en","type":"article","venue":"Cancer Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"","keywords":"Neural stem cell; Suicide gene; Stem cell; Cancer research; Gene; Gene delivery; Brain tumor; Dual (grammatical number); Medicine; Biology; Pathology; Genetic enhancement; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005744481,0.0003426108,0.0003020052,0.0000920566,0.0001655295,0.0000363183,0.0003428811,0.0001094172,0.0001389965],"category_scores_gemma":[0.00001159723,0.0003166931,0.0002464985,0.0001635159,0.000113049,0.00001175792,0.0000485915,0.0001249972,0.0000146165],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007795938,"about_ca_system_score_gemma":0.0003945139,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005198065,"about_ca_topic_score_gemma":0.00008440125,"domain_scores_codex":[0.9978154,0.0002354457,0.0003052401,0.0004757777,0.0002800048,0.0008880977],"domain_scores_gemma":[0.9987416,0.00009147472,0.0001263219,0.0005957914,0.0001654931,0.0002793311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004114015,0.0001499014,0.0009422309,0.00002682109,0.0001503691,0.000003278843,0.00009083477,0.002091392,0.9652582,0.000001970678,0.003295017,0.02387598],"study_design_scores_gemma":[0.003082315,0.00227243,0.0004848582,0.000006247544,0.0000224178,0.000007147527,0.00004570639,0.0004703615,0.9820026,0.00001042604,0.01120757,0.0003879335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9596894,0.03681768,0.001435057,0.0006313762,0.0003016527,0.0008428274,0.0002251574,0.00003181488,0.00002497034],"genre_scores_gemma":[0.9903513,0.001090412,0.0007258494,0.00503954,0.000951774,0.000632491,0.0002701075,0.0001268251,0.0008117291],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03572727,"threshold_uncertainty_score":0.9999285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.050248523801936,"score_gpt":0.3364228925924405,"score_spread":0.2861743687905045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}