{"id":"W2028923786","doi":"10.1371/journal.pone.0085856","title":"Complex Intra-Operonic Dynamics Mediated by a Small RNA in Streptomyces coelicolor","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Streptomyces coelicolor; Actinorhodin; Sigma factor; Biology; RNase P; Genetics; Transfer RNA; Gene; RNA; Streptomyces; Non-coding RNA; Transcription (linguistics); Gene expression; Mutant; RNA polymerase; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008894163,0.0003172568,0.000257566,0.0002288555,0.0001637809,0.0003278833,0.0001296978,0.0001544034,0.0004378611],"category_scores_gemma":[0.0001795817,0.0001058325,0.0002081759,0.0001456063,0.0002504622,0.0001117818,0.0001901952,0.0002376489,0.0003112282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003041934,"about_ca_system_score_gemma":0.0001972234,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001214477,"about_ca_topic_score_gemma":0.001301821,"domain_scores_codex":[0.9998373,0.00002623163,0.00001305775,0.00005252321,0.00004896346,0.00002179841],"domain_scores_gemma":[0.999721,0.0000591773,0.0001083244,0.00003149315,0.00002283107,0.00005714476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005121192,0.000009171639,0.0003580966,0.00001467428,0.000001822262,0.00004270673,0.00001343072,0.0000938712,0.9987509,0.00006199681,0.000008795114,0.0005933714],"study_design_scores_gemma":[0.00001326722,0.0003144588,0.01785913,0.000006168811,0.00001570596,0.0002561437,0.00007453396,0.002890576,0.9766261,0.0001147776,0.001814976,0.0000141443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953709,0.0005097559,0.002908697,0.00002746351,0.000009946774,0.000008902687,0.0002053671,0.00009184182,0.0008670665],"genre_scores_gemma":[0.9959381,0.0002040044,0.002321291,0.00001618375,0.000006763495,0.00001197703,0.0004459795,0.00002734651,0.001028356],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001214477,"threshold_uncertainty_score":0.002414882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03443273640467601,"score_gpt":0.2238717245999026,"score_spread":0.1894389881952266,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}