{"id":"W2028998458","doi":"10.1073/pnas.1415219111","title":"Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":322,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"","keywords":"Neurogenesis; Hippocampal formation; Adiponectin; Antidepressant; Endocrinology; Internal medicine; Adipogenesis; Adipocyte; Hormone; Receptor; Physical exercise; Hippocampus; Neuroscience; Medicine; Psychology; Obesity; Adipose tissue; Insulin resistance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005381536,0.0002533998,0.0001430791,0.0001269556,0.000103079,0.0001253926,0.00008594179,0.00008724563,0.0006651972],"category_scores_gemma":[0.00005257822,0.00009966329,0.0001938638,0.00008120378,0.0001969316,0.00009359093,0.0001444208,0.0003930994,0.000102801],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001014376,"about_ca_system_score_gemma":0.0001012264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004857132,"about_ca_topic_score_gemma":0.001439765,"domain_scores_codex":[0.9999694,0.000004667988,0.000003824141,0.000007965962,0.000006352182,0.000007838828],"domain_scores_gemma":[0.9999721,0.000002743127,0.00001119434,0.000004235793,0.000002737031,0.000007025299],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007634084,0.0001354025,0.001004564,0.0001404954,0.00004830749,0.0001030986,0.0000412552,0.00008016949,0.982145,0.0001557842,0.0001041469,0.01527847],"study_design_scores_gemma":[0.000437734,0.003077886,0.2731373,0.00008250192,0.0002485594,0.0007202101,0.0001728661,0.001281123,0.7138586,0.0006393468,0.006323227,0.00002072855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992402,0.003893771,0.001556139,0.0001370641,0.00003342892,0.00001777491,0.000177332,0.0000318745,0.001750542],"genre_scores_gemma":[0.9934978,0.003669198,0.001158069,0.00009078324,0.00001533956,0.00003588967,0.0001900872,0.000005275458,0.001337484],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006651972,"threshold_uncertainty_score":0.00222528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02331279804376725,"score_gpt":0.2884137010145155,"score_spread":0.2651009029707482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}