{"id":"W2029019611","doi":"10.1016/j.jchromb.2006.08.032","title":"Exploiting heparin-binding properties of MoMLV-based retroviral vectors for affinity chromatography","year":2006,"lang":"en","type":"article","venue":"Journal of Chromatography B","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Biotechnology Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Retrovirus; Affinity chromatography; Chemistry; Heparin; Cell culture; Murine leukemia virus; Chromatography; Virology; Biochemistry; Biology; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004138886,0.0003403708,0.0002366283,0.0003052412,0.0002533314,0.0007785967,0.0004914808,0.0003693174,0.001031153],"category_scores_gemma":[0.0004504332,0.000207581,0.0002740617,0.0002480406,0.0002832856,0.0003518239,0.0003041484,0.000958636,0.0006923794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000517057,"about_ca_system_score_gemma":0.0002982441,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001237603,"about_ca_topic_score_gemma":0.001851248,"domain_scores_codex":[0.9997433,0.00005483388,0.00001817437,0.00002629268,0.00009870955,0.00005876256],"domain_scores_gemma":[0.9997452,0.00008745581,0.00003601976,0.00003922427,0.00004672382,0.00004539182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003367977,0.00001941436,0.0001422715,0.00001642062,0.000004487126,0.00002919084,0.00001523652,0.00003436928,0.9971151,0.0003562243,0.00004625364,0.002187396],"study_design_scores_gemma":[0.000004373014,0.00004470355,0.0007417684,0.000003111976,0.000008770189,0.0001179712,0.00001054433,0.0009240123,0.9963061,0.000096072,0.001739174,0.00000337654],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8945163,0.002456754,0.097616,0.0005806485,0.00007323142,0.0001135818,0.0003192711,0.0003878219,0.003936292],"genre_scores_gemma":[0.964449,0.001091593,0.02804491,0.0001378661,0.00002408867,0.00004944867,0.0009015946,0.0000890431,0.005212379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001237603,"threshold_uncertainty_score":0.003751516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02130612015778093,"score_gpt":0.2643152258518308,"score_spread":0.2430091056940498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}