{"id":"W2029066749","doi":"10.1371/journal.ppat.1000708","title":"Bacterial Effector Binding to Ribosomal Protein S3 Subverts NF-κB Function","year":2009,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Michael Smith Health Research BC; University of British Columbia","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Institutes of Health; McMaster University","keywords":"Effector; Biology; Type three secretion system; Secretion; Microbiology; Shigella; Yersinia enterocolitica; Protein subunit; Virulence; Enteropathogenic Escherichia coli; Yersinia; Escherichia coli; Cell biology; Gene; Bacteria; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002723771,0.0004011389,0.0002449107,0.0001618241,0.0001806308,0.000314824,0.0002041455,0.000305974,0.001540065],"category_scores_gemma":[0.0001779609,0.0001095924,0.000469322,0.0001038554,0.0003826981,0.0001732396,0.0002633423,0.0004734369,0.0007801006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002761226,"about_ca_system_score_gemma":0.0002359951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004208277,"about_ca_topic_score_gemma":0.0005396285,"domain_scores_codex":[0.9997748,0.00004917176,0.0000191353,0.00003978733,0.00006594168,0.00005124843],"domain_scores_gemma":[0.9998142,0.00003555331,0.00005521034,0.00003176322,0.00002273321,0.00004055215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001043279,0.00001815033,0.0002781299,0.00004359264,0.00000403267,0.00008169888,0.00001446223,0.0000309134,0.998556,0.00007732639,0.00003605571,0.0007553289],"study_design_scores_gemma":[0.00003316745,0.0002715293,0.01281087,0.00002114974,0.00001305957,0.0007900744,0.00009196213,0.001286532,0.9797651,0.0001885325,0.004718953,0.000008976139],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918067,0.002715713,0.003384582,0.0001461564,0.00005825222,0.0000139292,0.0001851649,0.0001330469,0.001556254],"genre_scores_gemma":[0.996418,0.0005976711,0.001216603,0.000106797,0.00001138205,0.00001348762,0.0003573277,0.00002505227,0.001253575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001540065,"threshold_uncertainty_score":0.005152047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360912458755295,"score_gpt":0.2496488168502671,"score_spread":0.2360396922627142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}