{"id":"W2029066749","doi":"10.1371/journal.ppat.1000708","title":"Bacterial Effector Binding to Ribosomal Protein S3 Subverts NF-κB Function","year":2009,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":160,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Michael Smith Health Research BC; University of British Columbia","funders":"National Center for Research Resources; National Institute of Allergy and Infectious Diseases; National Institutes of Health; McMaster University","keywords":"Effector; Biology; Type three secretion system; Secretion; Microbiology; Shigella; Yersinia enterocolitica; Protein subunit; Virulence; Enteropathogenic Escherichia coli; Yersinia; Escherichia coli; Cell biology; Gene; Bacteria; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001606766,0.0001948777,0.0001768742,0.00006388805,0.0001583586,0.00004390095,0.0001557949,0.000127537,0.0000453167],"category_scores_gemma":[0.0004005213,0.0001808482,0.00009371321,0.0001650877,0.00002897708,0.000005484045,0.0001331298,0.0001033471,0.0001230263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003594163,"about_ca_system_score_gemma":0.00005831513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004207769,"about_ca_topic_score_gemma":0.0000171123,"domain_scores_codex":[0.9986145,0.0001144722,0.0001586344,0.0004286492,0.0002423186,0.0004413955],"domain_scores_gemma":[0.9993667,0.00001220453,0.00004330973,0.0003052048,0.0001061253,0.000166464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003298142,0.0001200124,0.001480239,0.00002007965,0.00005994237,0.00001163477,0.0000320429,0.000002376405,0.9954373,0.00002176615,0.001028675,0.001456166],"study_design_scores_gemma":[0.0005553805,0.00203272,0.0132267,0.0000401632,0.00003028279,0.000003386842,0.0000206131,0.00002094729,0.9704352,0.00002336778,0.01331055,0.0003006673],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977618,0.00008541211,0.0002538086,0.0003006905,0.0001559713,0.0007395015,0.00006712509,0.00004179162,0.0005938842],"genre_scores_gemma":[0.9969802,0.00001622738,0.001040051,0.0002278076,0.0007966318,0.0001414727,0.0001181354,0.00002465359,0.0006548112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02500203,"threshold_uncertainty_score":0.7374776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360912458755295,"score_gpt":0.2496488168502671,"score_spread":0.2360396922627142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}