{"id":"W2029137036","doi":"10.1523/jneurosci.1040-06.2006","title":"A Sex-Specific Role of Type VII Adenylyl Cyclase in Depression","year":2006,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Phosphodiesterase function and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health","keywords":"Adenylyl cyclase; Depression (economics); Major depressive disorder; Etiology; ADCY9; Psychology; Psychiatry; Medicine; Bioinformatics; Biology; Neuroscience; Cognition; Stimulation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001110021,0.00004570255,0.0000730258,0.00006008894,0.00002353806,0.000009495582,0.00009690245,0.00003673431,0.000003367129],"category_scores_gemma":[0.00003258765,0.00003583389,0.00003445068,0.0001331682,0.00005048947,0.000008885649,0.00002567059,0.00005594019,4.830196e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006411731,"about_ca_system_score_gemma":0.0000351643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003772842,"about_ca_topic_score_gemma":0.00000335996,"domain_scores_codex":[0.9994657,0.0000264501,0.0002040059,0.00009496708,0.0001340868,0.00007479388],"domain_scores_gemma":[0.9996657,0.000005365399,0.0001523952,0.00008703939,0.00006194998,0.0000275511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007327966,0.00005730062,0.01447034,0.000001622592,3.56115e-7,0.000005467343,0.00001017252,0.001238307,0.9824802,0.000008661883,0.0003413178,0.00131297],"study_design_scores_gemma":[0.0003241471,0.0002258922,0.2136201,0.00001681437,0.000001715396,0.00009904647,0.00002011506,0.0003816133,0.7528942,0.00007534332,0.03229247,0.00004850433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984152,0.000652008,0.0002980331,0.00002857696,0.000287949,0.0000254592,8.770925e-7,0.000001079863,0.0002907661],"genre_scores_gemma":[0.9993675,0.0001211613,0.0001037663,0.00005546803,0.00008835139,2.419302e-7,9.352068e-7,0.000003354016,0.0002591891],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.229586,"threshold_uncertainty_score":0.1461264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009302571058958051,"score_gpt":0.2365780763236514,"score_spread":0.2272755052646933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}