{"id":"W2029154036","doi":"10.1074/jbc.m100326200","title":"Interaction of Lecithin:Cholesterol Acyltransferase (LCAT)·α2-Macroglobulin Complex with Low Density Lipoprotein Receptor-related Protein (LRP)","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Clinical Research Institute; McGill University; Royal Victoria Hospital","funders":"Canadian Institutes of Health Research; Pfizer","keywords":"Phosphatidylcholine; Chemistry; High-density lipoprotein; Sterol O-acyltransferase; Lipoprotein lipase; Lipoprotein; Lecithin; Cholesterol; Acyltransferase; Biochemistry; Enzyme; Phospholipid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001620869,0.0004266909,0.0003230528,0.000184406,0.0002036818,0.0003621482,0.0002756539,0.0003712931,0.0009789291],"category_scores_gemma":[0.0002013694,0.0001638594,0.000276619,0.0001454976,0.0001674478,0.0001806603,0.0002988546,0.0003310946,0.0004438488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005394578,"about_ca_system_score_gemma":0.0001430656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001097008,"about_ca_topic_score_gemma":0.001017684,"domain_scores_codex":[0.9998307,0.00004079347,0.000007547249,0.00005246814,0.00003134654,0.00003715163],"domain_scores_gemma":[0.9999447,0.00001652763,0.00001206583,0.000005596887,0.000008411808,0.00001263074],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001894633,0.00002890639,0.00127891,0.00004232274,0.00003217709,0.0001595563,0.00003639097,0.00008517974,0.99687,0.00007227505,0.00006948251,0.001135413],"study_design_scores_gemma":[0.00003893491,0.0004403393,0.02060031,0.00001289269,0.00004104145,0.0008158882,0.00006026446,0.003442755,0.9701955,0.00007878174,0.004255261,0.00001798066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964578,0.001768233,0.001168004,0.00006078561,0.00002110288,0.00001572912,0.00005270785,0.00003169562,0.0004239262],"genre_scores_gemma":[0.9954449,0.0008981792,0.001481762,0.00007706894,0.00002028167,0.00001986696,0.0003233217,0.00001130357,0.001723434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001097008,"threshold_uncertainty_score":0.003913999,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.022119893712112,"score_gpt":0.2634464292440467,"score_spread":0.2413265355319347,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}