{"id":"W2029325974","doi":"10.1111/j.1600-0625.2009.00916.x","title":"Proliferative defects in dyskeratosis congenita skin keratinocytes are corrected by expression of the telomerase reverse transcriptase, TERT, or by activation of endogenous telomerase through expression of papillomavirus E6/E7 or the telomerase RNA component, TERC","year":2009,"lang":"en","type":"article","venue":"Experimental Dermatology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Telomerase; Dyskeratosis congenita; Telomerase reverse transcriptase; Telomere; Telomerase RNA component; Biology; Cancer research; Keratinocyte; Molecular biology; Cell biology; Cell culture; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001208242,0.0004914395,0.000167996,0.0005434818,0.0002160398,0.0002741785,0.0001532662,0.0003334027,0.002199495],"category_scores_gemma":[0.0001816828,0.000184366,0.0001666909,0.0001846062,0.0002005539,0.000149605,0.0001592822,0.0004540691,0.0006803281],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001649342,"about_ca_system_score_gemma":0.0001363273,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002005245,"about_ca_topic_score_gemma":0.0004259437,"domain_scores_codex":[0.9998515,0.00002158374,0.00002251214,0.00004037823,0.00004028231,0.00002377542],"domain_scores_gemma":[0.9998797,0.00002446093,0.00003467223,0.00002199416,0.000007766041,0.00003139585],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004515046,0.00004661356,0.0009750976,0.0000478535,0.000006627129,0.0009074994,0.00002900837,0.00003353526,0.9957969,0.00008502843,0.00008059118,0.001946019],"study_design_scores_gemma":[0.00003470329,0.0004101816,0.04884282,0.00002907643,0.0000763076,0.02185808,0.0001290569,0.000578408,0.9225398,0.0001650536,0.005322524,0.00001401156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950333,0.0009109275,0.0009828255,0.00004559671,0.00002216396,0.00002240515,0.0002235997,0.0001453563,0.00261383],"genre_scores_gemma":[0.9962269,0.0006122892,0.0007099361,0.0000253623,0.000009962889,0.00001453842,0.000262158,0.00001984543,0.002119031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002199495,"threshold_uncertainty_score":0.007358074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02929190512462596,"score_gpt":0.279534100279073,"score_spread":0.250242195154447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}