{"id":"W2029338166","doi":"10.1007/s10549-004-5780-0","title":"Detection of genetic instability at HER-2/neu and p53 loci in breast cancer cells sing Comet–FISH","year":2005,"lang":"en","type":"article","venue":"Breast Cancer Research and Treatment","topic":"Animal Genetics and Reproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"U.S. Department of Defense","keywords":"Breast cancer; Fish <Actinopterygii>; Comet assay; Biology; Microsatellite instability; Comet; Cancer; Oncology; Genetics; Gene; Cancer research; Medicine; DNA damage; DNA; Fishery; Microsatellite; Allele","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001628974,0.0001394096,0.0001600299,0.00007636837,0.0001339391,0.00001961698,0.00004978652,0.00009193703,0.00003382012],"category_scores_gemma":[0.000003156999,0.0001149503,0.00003481091,0.0001429685,0.0002423974,0.000005949246,0.000109686,0.00007439844,0.000001005759],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002567046,"about_ca_system_score_gemma":0.00008990479,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00428528,"about_ca_topic_score_gemma":0.01118074,"domain_scores_codex":[0.9987761,0.00007804872,0.0001843475,0.000490529,0.0001699992,0.0003009714],"domain_scores_gemma":[0.9994653,0.000008590596,0.00004804923,0.0002134213,0.0001437074,0.0001208943],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007186012,0.0002718566,0.09484509,0.00004088169,0.00005905279,0.000002169467,0.0000817597,0.0001620319,0.6769928,0.000001271269,0.00002994407,0.2267946],"study_design_scores_gemma":[0.0009978531,0.0004452103,0.6582547,0.00002371564,0.00001558897,0.00006518911,0.00006808711,0.0001036907,0.3371173,0.00001102792,0.002780978,0.0001166989],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931461,0.005381401,0.00001054823,0.0008763866,0.00003677202,0.0003149646,0.0001855232,0.000003834964,0.00004446677],"genre_scores_gemma":[0.9853711,0.01395526,0.00005443437,0.00001923797,0.0002314586,0.00009749253,0.00001075306,0.00001536905,0.0002448956],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5634096,"threshold_uncertainty_score":0.647809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02369822946897662,"score_gpt":0.3124005475729429,"score_spread":0.2887023181039663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}