{"id":"W2029384328","doi":"10.1016/j.chembiol.2005.12.003","title":"Biosynthesis of Sulfated Glycopeptide Antibiotics by Using the Sulfotransferase StaL","year":2006,"lang":"en","type":"article","venue":"Chemistry & Biology","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Glycopeptide; Teicoplanin; Sulfation; Glycopeptide antibiotic; Sulfotransferase; Biochemistry; Antibiotics; Biosynthesis; In vivo; Biology; Chemistry; Bacteria; Enzyme; Vancomycin; Staphylococcus aureus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001589543,0.0003643071,0.0004644305,0.00001654129,0.0001548342,0.00001995341,0.0005290858,0.0004860589,0.00176382],"category_scores_gemma":[0.0001198284,0.0002892489,0.0002416186,0.0002174422,0.0007068969,0.00004086488,0.00008367205,0.0002816537,0.000005514467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008179331,"about_ca_system_score_gemma":0.00008991151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003838087,"about_ca_topic_score_gemma":0.000005779682,"domain_scores_codex":[0.9982156,0.00003073232,0.0006005956,0.0005007997,0.0001461113,0.0005061639],"domain_scores_gemma":[0.998593,0.0003016278,0.0002198122,0.0006886935,0.0001095426,0.00008732067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007181762,0.000153388,0.004349035,0.0002300858,0.00007941374,0.000009584415,0.00002053543,0.00002378792,0.9943238,0.00001434259,0.0004714656,0.0002527306],"study_design_scores_gemma":[0.0003510654,0.000005856726,0.00002134085,0.00005484336,0.0001019936,0.00004049701,0.0001677192,0.0002562632,0.995571,0.00008003716,0.00302444,0.0003249452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881704,0.0006991876,0.00006930246,0.0001228436,0.00004175044,0.0000483613,0.0008426816,0.00008264949,0.009922785],"genre_scores_gemma":[0.9981107,0.00006402823,0.00009886368,0.00002254016,0.0002506801,0.000001862566,0.0004373554,0.0000393231,0.0009746057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009940303,"threshold_uncertainty_score":0.999956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01005151231363314,"score_gpt":0.2223398616137309,"score_spread":0.2122883493000978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}