{"id":"W2029402099","doi":"10.1371/journal.pbio.0060109","title":"Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System","year":2008,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Congenital heart defects research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":276,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Sarnoff Cardiovascular Research Foundation; U.S. Public Health Service; GlaxoSmithKline; David and Lucile Packard Foundation","keywords":"Biology; Zebrafish; Electrical conduction system of the heart; Danio; Vertebrate; Ventricle; Cell biology; Homeobox; Anatomy; Genetics; Bioinformatics; Neuroscience; Internal medicine; Transcription factor; Gene; Electrocardiography; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002243511,0.0006263114,0.0001981844,0.000671109,0.0004058716,0.0003528725,0.0004260438,0.0004834298,0.001077855],"category_scores_gemma":[0.000168669,0.0003125356,0.0002816264,0.000194346,0.0007241019,0.0004113243,0.000450252,0.0008741319,0.0003044849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000547812,"about_ca_system_score_gemma":0.0007203528,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002568593,"about_ca_topic_score_gemma":0.003522759,"domain_scores_codex":[0.9998145,0.00001720636,0.00002336407,0.00005506706,0.00006449022,0.00002549518],"domain_scores_gemma":[0.9998531,0.00003199619,0.00004203976,0.00001871474,0.00001714829,0.00003683969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001259056,0.000005234935,0.0001631426,0.00002519747,0.00000180635,0.00009742607,0.00001162605,0.0001403692,0.9973915,0.001010628,0.00002130449,0.001119259],"study_design_scores_gemma":[0.00003572047,0.0003498109,0.02461854,0.00006603682,0.00006602801,0.002459672,0.00009886884,0.004716775,0.948022,0.001401659,0.01812925,0.00003572592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9197465,0.005140602,0.06296025,0.0006448497,0.0000779781,0.0001822298,0.001767141,0.0003353046,0.009145156],"genre_scores_gemma":[0.9332814,0.005855809,0.0538256,0.0002305962,0.0000450258,0.000149997,0.001205716,0.0001157065,0.005290119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002568593,"threshold_uncertainty_score":0.005107284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02032419418182434,"score_gpt":0.2435002806312315,"score_spread":0.2231760864494072,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}