{"id":"W2029411138","doi":"10.4161/cc.10.10.15520","title":"Multiple pathways counteract cell death induced by RB1 loss: Implications for cancer","year":2011,"lang":"en","type":"article","venue":"Cell Cycle","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Biology; Autophagy; Myogenesis; Programmed cell death; Cell biology; Cancer cell; Apoptosis; Suppressor; Cancer research; Neoplastic transformation; Cancer; Myocyte; Genetics; Carcinogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000592079,0.0001366735,0.0001739488,0.00003231189,0.0001047272,0.00001127296,0.000116255,0.00008387261,0.0004577378],"category_scores_gemma":[0.00001173426,0.0001217837,0.0001054865,0.00006396799,0.00002272379,0.00007123948,0.00001681187,0.00009253959,0.00008122715],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006047548,"about_ca_system_score_gemma":0.0001097381,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003028977,"about_ca_topic_score_gemma":0.00001184579,"domain_scores_codex":[0.99924,0.00001371702,0.0001719722,0.000245329,0.00007595413,0.0002529688],"domain_scores_gemma":[0.9992449,0.00006517847,0.00008063406,0.0003527454,0.0000836059,0.0001729799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003658319,0.001677888,0.05615193,0.0001541451,0.0000826847,0.000008292714,0.001705918,0.000002247664,0.924993,0.0002678697,0.01032661,0.004263594],"study_design_scores_gemma":[0.003925084,0.0002883624,0.07807399,0.00003768721,0.0001622921,0.000003189565,0.0001451669,0.0005731668,0.8895044,0.001454649,0.02553867,0.0002933585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882925,0.001052055,0.000493313,0.0001233658,0.0001392578,0.0005987564,0.0002945227,0.0000823431,0.008923844],"genre_scores_gemma":[0.9970187,0.0001712888,0.0003250434,0.001026402,0.0001254644,0.0003383855,0.0001197938,0.00004083555,0.00083411],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0354886,"threshold_uncertainty_score":0.5011908,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05032834129676229,"score_gpt":0.2970034970932455,"score_spread":0.2466751557964832,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}