{"id":"W2029445482","doi":"10.1371/journal.pone.0111229","title":"Efficient Production of sTNFRII-gAD Fusion Protein in Large Quantity by Use of the Modified CHO-S Cell Expression System","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Viral Infectious Diseases and Gene Expression in Insects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Natural Science Foundation of Zhejiang Province; Zhejiang Provincial Program for the Cultivation of High-Level Innovative Health Talents","keywords":"Chinese hamster ovary cell; Fusion protein; Recombinant DNA; Receptor; Cell culture; Biology; Chemistry; Molecular biology; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003730427,0.0006251798,0.0009965241,0.0003607695,0.0002133602,0.0005087483,0.0005967461,0.0004529218,0.0009300932],"category_scores_gemma":[0.0002305258,0.0002410983,0.000556578,0.0006251315,0.000212065,0.0002560628,0.0004355969,0.0009128072,0.00119148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004512723,"about_ca_system_score_gemma":0.0002910025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000591584,"about_ca_topic_score_gemma":0.0007008731,"domain_scores_codex":[0.9996293,0.00005535142,0.00005782905,0.00007218305,0.0001314228,0.00005396324],"domain_scores_gemma":[0.9998701,0.00001839732,0.00002684802,0.00002905167,0.00003331617,0.00002225185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002674173,0.00001422175,0.00004245969,0.0000349161,0.00000508452,0.00002857326,0.00001453115,0.00004552789,0.9989556,0.00005960952,0.00005292723,0.0007196699],"study_design_scores_gemma":[0.00001996873,0.00013281,0.0006935216,0.000006726173,0.0000251117,0.000269452,0.0000190414,0.001491648,0.9903195,0.00004271705,0.006968913,0.00001058921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8922325,0.004601083,0.09295068,0.0004777734,0.0002669899,0.0004274493,0.003658751,0.0009430173,0.004441814],"genre_scores_gemma":[0.8530934,0.003869387,0.1192242,0.0002147017,0.00007676672,0.0004615366,0.01308738,0.0003040936,0.009668616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009965241,"threshold_uncertainty_score":0.003274202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01800928474848158,"score_gpt":0.2104454755463818,"score_spread":0.1924361907979002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}