{"id":"W2029452753","doi":"10.1002/jgm.576","title":"Combined alpha tumor necrosis factor gene therapy and engineered dendritic cell vaccine in combating well‐established tumors","year":2004,"lang":"en","type":"article","venue":"The Journal of Gene Medicine","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Tumor necrosis factor alpha; Immune system; Genetic enhancement; CTL*; Immunotherapy; Cancer research; Cytotoxic T cell; Medicine; Immunology; Dendritic cell; Cytokine; Biology; CD8; Gene; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001151499,0.0002805018,0.0007081929,0.0003230616,0.0001763194,0.00001402138,0.0004075473,0.0001031333,0.0003781947],"category_scores_gemma":[0.0001905493,0.0001662087,0.00008169509,0.000304538,0.0002235164,0.0001390464,0.00003755468,0.0006166912,0.00001287735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007372621,"about_ca_system_score_gemma":0.000124213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002322281,"about_ca_topic_score_gemma":0.000008907843,"domain_scores_codex":[0.9980384,0.0004301602,0.0008876427,0.000140745,0.0001052521,0.0003978193],"domain_scores_gemma":[0.9985331,0.0005592612,0.0004489029,0.0002779858,0.0001378323,0.00004287626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002937116,0.0001845677,0.001049718,0.00001618198,0.0001433741,0.0000450026,0.003326205,0.00006527262,0.9907585,0.00001377615,0.0002333795,0.001226875],"study_design_scores_gemma":[0.02436842,0.003340111,0.06997741,0.0003105011,0.0000746548,0.001386547,0.001327874,0.000006470548,0.8977917,0.0001621703,0.001033019,0.0002210992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.949065,0.04768473,0.0002225628,0.002120228,0.0005974836,0.0002460809,0.000004627885,0.00001624085,0.00004309847],"genre_scores_gemma":[0.993662,0.004997734,0.0001517365,0.0007014971,0.00008447911,0.00000338735,0.000009148197,0.0000330344,0.0003569958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09296681,"threshold_uncertainty_score":0.6777796,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01201082584653061,"score_gpt":0.2270339943558255,"score_spread":0.2150231685092949,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}