{"id":"W2029479476","doi":"10.1371/journal.ppat.1002238","title":"Burkholderia cenocepacia BC2L-C Is a Super Lectin with Dual Specificity and Proinflammatory Activity","year":2011,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"European Regional Development Fund; Canadian Institutes of Health Research; National Institute of General Medical Sciences; Centre National de la Recherche Scientifique; Austrian Science Fund; Central European Institute of Technology; Grantová Agentura České Republiky; European Synchrotron Radiation Facility; Cystic Fibrosis Canada","keywords":"Mannose; Biology; Lectin; Proinflammatory cytokine; Glycoconjugate; Mannan-binding lectin; Biochemistry; Burkholderia cenocepacia; Bacterial adhesin; C-type lectin; Yersinia pseudotuberculosis; Epitope; Fucose; Microbiology; Cell biology; Glycoprotein; Escherichia coli; Immunology; Inflammation; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001236609,0.0002150286,0.0002043146,0.00003926348,0.0001492471,0.00002960735,0.00009886448,0.0001112367,0.0001022848],"category_scores_gemma":[0.00007155374,0.0001765443,0.00004884608,0.00007560525,0.0002100308,0.000009571704,0.0002243276,0.0001252781,0.00001720608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001724483,"about_ca_system_score_gemma":0.0000840386,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002764324,"about_ca_topic_score_gemma":0.00010441,"domain_scores_codex":[0.9987435,0.0000798555,0.0001197076,0.0004897172,0.000182985,0.0003842325],"domain_scores_gemma":[0.9993175,0.000009044322,0.00005276755,0.0003680698,0.0001154768,0.0001370952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003366191,0.000138451,0.03151497,0.00004050837,0.0001591834,0.00004178754,0.0006939438,4.809653e-8,0.9661865,0.000008591951,0.0004864744,0.0003929576],"study_design_scores_gemma":[0.0004739451,0.0005191544,0.1510503,0.00001570881,0.00003352425,0.00003583344,0.0001656018,0.00000674632,0.845212,0.00001759749,0.002204945,0.0002646174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971706,0.0001443561,0.00004776517,0.00008254233,0.00003735051,0.0003381094,0.00007466412,0.00002701418,0.002077576],"genre_scores_gemma":[0.9980317,0.0001701249,0.00103106,0.00005222584,0.0001670131,0.00005125685,0.00001312321,0.00003552163,0.0004479314],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1209745,"threshold_uncertainty_score":0.7199267,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03533920869403068,"score_gpt":0.2284040962912247,"score_spread":0.193064887597194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}