{"id":"W2029479476","doi":"10.1371/journal.ppat.1002238","title":"Burkholderia cenocepacia BC2L-C Is a Super Lectin with Dual Specificity and Proinflammatory Activity","year":2011,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Vibrio bacteria research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"European Regional Development Fund; Canadian Institutes of Health Research; National Institute of General Medical Sciences; Centre National de la Recherche Scientifique; Austrian Science Fund; Central European Institute of Technology; Grantová Agentura České Republiky; European Synchrotron Radiation Facility; Cystic Fibrosis Canada","keywords":"Mannose; Biology; Lectin; Proinflammatory cytokine; Glycoconjugate; Mannan-binding lectin; Biochemistry; Burkholderia cenocepacia; Bacterial adhesin; C-type lectin; Yersinia pseudotuberculosis; Epitope; Fucose; Microbiology; Cell biology; Glycoprotein; Escherichia coli; Immunology; Inflammation; Antigen","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001174372,0.0004953586,0.0001976198,0.0002493162,0.0002226417,0.0003755591,0.0001471632,0.0003394113,0.0003266708],"category_scores_gemma":[0.0001153936,0.00009306141,0.0001484253,0.0003096791,0.0002002749,0.0001760122,0.0002479616,0.0002633668,0.0002134794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005012634,"about_ca_system_score_gemma":0.000272515,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002811752,"about_ca_topic_score_gemma":0.002481456,"domain_scores_codex":[0.9998263,0.00002668252,0.0000102123,0.00003674417,0.00005517227,0.00004487284],"domain_scores_gemma":[0.9999048,0.000006860126,0.00002130979,0.000008293179,0.00002193371,0.00003678956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005615009,0.00001716868,0.0009273893,0.00002380033,0.000003579979,0.0001127955,0.000006920527,0.00005398805,0.9977919,0.00003694087,0.00003920319,0.0009302592],"study_design_scores_gemma":[0.00003746348,0.0005813456,0.04632569,0.00001489606,0.00003170147,0.004958254,0.000105119,0.003308668,0.9301087,0.000150406,0.01435258,0.00002510097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928755,0.002862385,0.002658153,0.000157954,0.00001864026,0.00002479089,0.0004466767,0.00005696418,0.0008990542],"genre_scores_gemma":[0.9942326,0.0007884778,0.002620447,0.0000937705,0.00001305301,0.00001341703,0.0009854961,0.000007108451,0.001245663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002811752,"threshold_uncertainty_score":0.005590737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03533920869403068,"score_gpt":0.2284040962912247,"score_spread":0.193064887597194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}