{"id":"W2029598106","doi":"10.1111/j.1399-3038.2005.00240.x","title":"Population pharmacokinetics of levocetirizine in very young children: the pediatricians’ perspective","year":2005,"lang":"en","type":"article","venue":"Pediatric Allergy and Immunology","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Levocetirizine; Medicine; Cetirizine; Population; Pharmacokinetics; Dosing; Pharmacodynamics; NONMEM; Pharmacology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001647495,0.000262485,0.0009585853,0.000346151,0.00007701894,0.0007896741,0.0002627877,0.0005088181,0.0004206644],"category_scores_gemma":[0.00386597,0.0002040684,0.0005735333,0.0003028186,0.000344622,0.000594276,0.0002762414,0.001032892,0.0001054467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005685788,"about_ca_system_score_gemma":0.0006417062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003572182,"about_ca_topic_score_gemma":0.002861425,"domain_scores_codex":[0.9995381,0.0002280345,0.00004495484,0.00008446012,0.00007420614,0.00003036021],"domain_scores_gemma":[0.9982546,0.001074266,0.0003282556,0.00006691986,0.0001951591,0.00008088684],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001474724,0.0001687663,0.6522577,0.001182026,0.001574915,0.002873299,0.0008719655,0.01513303,0.01050422,0.004217292,0.006017896,0.3037242],"study_design_scores_gemma":[0.0002041096,0.005071511,0.8795884,0.00076775,0.001807847,0.01385796,0.00165101,0.01738248,0.007783376,0.007846464,0.06390628,0.0001327684],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6954677,0.2492398,0.03001394,0.0179163,0.000232047,0.00006519756,0.001872284,0.0002119015,0.004980859],"genre_scores_gemma":[0.8897161,0.09909405,0.007824511,0.001837575,0.0005956872,0.00005670608,0.0004271478,0.00002702417,0.0004211272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003572182,"threshold_uncertainty_score":0.008712828,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0166404441511465,"score_gpt":0.3089659143506504,"score_spread":0.2923254701995038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}