{"id":"W2029622368","doi":"10.1128/aac.05175-11","title":"A Novel Target-Specific, Salt-Resistant Antimicrobial Peptide against the Cariogenic Pathogen Streptococcus mutans","year":2011,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Marine Biosciences; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Atlantic Canada Opportunities Agency; China Scholarship Council; Canadian Institutes of Health Research; Dalhousie University","keywords":"Streptococcus mutans; Streptococcus gordonii; Microbiology; Streptococcus sanguinis; Peptide; Antimicrobial; Pathogen; Chemistry; Saliva; Mutant; Biofilm; Antimicrobial peptides; Biology; Bacteria; Biochemistry; Streptococcaceae; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000138092,0.0003401196,0.0003414999,0.000146809,0.00009851591,0.0003373387,0.000274919,0.0004270737,0.0004580587],"category_scores_gemma":[0.00014238,0.00008278543,0.000219464,0.0001033359,0.0001744435,0.000270612,0.0002339937,0.0004868082,0.0002108889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001518513,"about_ca_system_score_gemma":0.0001710529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001581324,"about_ca_topic_score_gemma":0.0002370849,"domain_scores_codex":[0.9998795,0.00001695133,0.000009406007,0.00002545733,0.00004653872,0.00002214333],"domain_scores_gemma":[0.999907,0.00001258071,0.00002546721,0.000006722202,0.00002047654,0.0000276387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003059505,0.00002157041,0.0001216392,0.00004227185,0.000003196306,0.00004816938,0.000007620753,0.0001075247,0.9978168,0.00003121235,0.00001009385,0.001759206],"study_design_scores_gemma":[0.0000197074,0.001275348,0.001330615,0.00000766156,0.00001987815,0.0007314956,0.0000243143,0.0009237552,0.99243,0.00003075178,0.003197748,0.000008630553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900613,0.002053504,0.006803254,0.00009909434,0.0000352161,0.00007730999,0.0001083567,0.0000492511,0.0007127399],"genre_scores_gemma":[0.9833424,0.001062724,0.01353355,0.0001222317,0.00002408439,0.00006216227,0.0003029473,0.00001736941,0.001532545],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004580587,"threshold_uncertainty_score":0.001532376,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02084977372598796,"score_gpt":0.2159914364613027,"score_spread":0.1951416627353148,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}