{"id":"W2029634411","doi":"10.1007/s12079-008-0029-z","title":"Regulation of CCN2 mRNA expression and promoter activity in activated hepatic stellate cells","year":2008,"lang":"en","type":"article","venue":"Journal of Cell Communication and Signaling","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; National Institute on Alcohol Abuse and Alcoholism; Arthritis Society","keywords":"Hepatic stellate cell; CTGF; SMAD; Molecular biology; Transforming growth factor; Growth factor; Hepatic fibrosis; Cell biology; Biology; Receptor; Fibrosis; Chemistry; Pathology; Medicine; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004068067,0.00006389558,0.000136662,0.00009182785,0.00005778991,0.000008911762,0.0001034516,0.00006616137,0.00001107471],"category_scores_gemma":[0.00004618189,0.00005713144,0.0000276896,0.00006615154,0.00006574825,0.00001747327,0.00008736111,0.0001547679,1.460623e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001246155,"about_ca_system_score_gemma":0.00003566793,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001498416,"about_ca_topic_score_gemma":0.000003896344,"domain_scores_codex":[0.9992282,0.0002679846,0.00023121,0.00007932218,0.0001198072,0.00007344694],"domain_scores_gemma":[0.9993097,0.00007459632,0.0002624427,0.0001712191,0.0001383052,0.00004378571],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001850676,0.00006314061,0.004885945,0.00003227562,0.000007914516,0.000001032926,0.0004068245,0.00006116128,0.9934396,0.000001045706,0.000008038836,0.0009079677],"study_design_scores_gemma":[0.000632265,0.000150888,0.02076202,0.00007857091,0.000004491314,0.00001396436,0.00006085901,0.0003136143,0.9777884,0.0000500434,0.00009101952,0.00005387218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985315,0.0008608189,0.0003358428,0.00004362375,0.000008942073,0.0000957234,7.505628e-7,0.000001097396,0.0001216554],"genre_scores_gemma":[0.9979374,0.001179975,0.0008091364,0.000005283742,0.00001196802,8.533258e-7,0.00000239395,0.000006922423,0.00004606397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01587608,"threshold_uncertainty_score":0.2329752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02619082386964361,"score_gpt":0.2755707071193549,"score_spread":0.2493798832497113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}