{"id":"W2029634411","doi":"10.1007/s12079-008-0029-z","title":"Regulation of CCN2 mRNA expression and promoter activity in activated hepatic stellate cells","year":2008,"lang":"en","type":"article","venue":"Journal of Cell Communication and Signaling","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; National Institute on Alcohol Abuse and Alcoholism; Arthritis Society","keywords":"Hepatic stellate cell; CTGF; SMAD; Molecular biology; Transforming growth factor; Growth factor; Hepatic fibrosis; Cell biology; Biology; Receptor; Fibrosis; Chemistry; Pathology; Medicine; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002273273,0.0002242427,0.0001910227,0.0003387665,0.0001432861,0.0002790699,0.00005778865,0.000147292,0.001235408],"category_scores_gemma":[0.0002124178,0.000116006,0.0002063853,0.0001587557,0.0002782659,0.0001187787,0.0001707799,0.00028585,0.0003665562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003602562,"about_ca_system_score_gemma":0.0001966525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000433422,"about_ca_topic_score_gemma":0.0009686092,"domain_scores_codex":[0.9997435,0.00006917534,0.00002074439,0.00005642089,0.0000651294,0.00004502996],"domain_scores_gemma":[0.9997907,0.00006159501,0.00004499486,0.00002490029,0.00003495479,0.00004276746],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000708185,0.000006449946,0.0002143612,0.00001597499,0.000001693417,0.00002083119,0.0000222846,0.00003516291,0.9989164,0.00007198574,0.00001767235,0.000606371],"study_design_scores_gemma":[0.00001349755,0.0001280206,0.006948183,0.000006147638,0.000007007538,0.0001484668,0.0000427618,0.001066876,0.9894951,0.00006045927,0.002078976,0.000004549441],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890443,0.002778772,0.005016851,0.0001121709,0.0000419688,0.0000355744,0.0007142382,0.00009359135,0.002162523],"genre_scores_gemma":[0.9877875,0.001260373,0.005595906,0.00007053516,0.00002599386,0.0001107471,0.001198836,0.00003677392,0.003913276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001235408,"threshold_uncertainty_score":0.004132807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02619082386964361,"score_gpt":0.2755707071193549,"score_spread":0.2493798832497113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}