{"id":"W2029636772","doi":"10.1194/jlr.m800204-jlr200","title":"The level and compartmentalization of phosphatidate phosphatase-1 (lipin-1) control the assembly and secretion of hepatic VLDL","year":2008,"lang":"en","type":"article","venue":"Journal of Lipid Research","topic":"Lipid metabolism and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Ottawa","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; State University of New York; SUNY Downstate Medical Center; Heart and Stroke Foundation of Canada","keywords":"Compartmentalization (fire protection); Secretion; Very low-density lipoprotein; Chemistry; Phosphatidate; Cell biology; Endocrinology; Internal medicine; Phosphatase; Biochemistry; Biology; Cholesterol; Lipoprotein; Medicine; Phosphorylation; Enzyme; Protein kinase C; Diacylglycerol kinase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001953691,0.00007762101,0.0001927469,0.00005004785,0.0002457147,0.0000198693,0.0001947413,0.00005760909,0.000004703926],"category_scores_gemma":[0.0003570655,0.00004076268,0.00005429684,0.0001094434,0.0004690367,0.00001198828,0.00007601402,0.0001189841,4.170701e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006474852,"about_ca_system_score_gemma":0.000119256,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001963368,"about_ca_topic_score_gemma":0.00001062893,"domain_scores_codex":[0.9985778,0.0003412016,0.0003969151,0.00009762868,0.0004258303,0.0001605727],"domain_scores_gemma":[0.9988099,0.000221172,0.0003004796,0.0001751449,0.0004284504,0.00006488022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0011001,0.0001875233,0.0383987,0.0001021587,0.0002803613,0.000002811136,0.0004547999,0.0000170747,0.9435616,0.0004025813,0.004748943,0.01074341],"study_design_scores_gemma":[0.001258891,0.0004623474,0.05899395,0.00005110963,0.00003853001,0.00006881879,0.0003208399,0.0002929475,0.911895,0.00003711321,0.02651368,0.00006679758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9893913,0.009395051,0.0003829633,0.0004643767,0.0001154408,0.0001704918,0.00002966651,6.808723e-7,0.00005003831],"genre_scores_gemma":[0.9910099,0.008426157,0.0001610661,0.00003318813,0.0002678398,0.000003041486,0.000007716949,0.000007248781,0.00008386859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03166656,"threshold_uncertainty_score":0.1889864,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04863235301840857,"score_gpt":0.3160807220043076,"score_spread":0.267448368985899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}