{"id":"W2029653712","doi":"10.1016/j.neuropharm.2008.05.033","title":"Up-regulation of protein l-isoaspartyl methyltransferase expression by lithium is mediated by glycogen synthase kinase-3 inactivation and β-catenin stabilization","year":2008,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"GSK-3; GSK3B; Glycogen synthase; Methyltransferase; Chemistry; Lithium (medication); Catenin; ATP synthase; Kinase; Cell biology; Enzyme; Biochemistry; Endocrinology; Biology; Signal transduction; Gene; Wnt signaling pathway; Methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001603997,0.0004319526,0.0004165588,0.0003962315,0.0002607256,0.0005154629,0.0003376903,0.0002835564,0.001657293],"category_scores_gemma":[0.0001696456,0.0001996444,0.0004301594,0.0002386541,0.0004285394,0.0003546385,0.0003348645,0.0004669527,0.0004242712],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009232562,"about_ca_system_score_gemma":0.0004548001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001577112,"about_ca_topic_score_gemma":0.002423541,"domain_scores_codex":[0.9998504,0.00002166462,0.00002070745,0.00002858707,0.00002987204,0.00004873605],"domain_scores_gemma":[0.9998763,0.0000129299,0.00004653196,0.00001629568,0.00001507455,0.00003305024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006044984,0.00002966618,0.0002504912,0.00002333681,0.000005988143,0.00004966261,0.0000108374,0.00001459314,0.9977528,0.0001525549,0.00007293458,0.001032719],"study_design_scores_gemma":[0.00003466582,0.00012627,0.002570033,0.000002807724,0.00001519446,0.00009547555,0.00001755131,0.000269456,0.9956399,0.00004765569,0.0011756,0.000005355312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918828,0.002685696,0.002124686,0.0003523545,0.00007152456,0.00003039889,0.0005688615,0.0003967564,0.001886882],"genre_scores_gemma":[0.9947865,0.0006090278,0.0008963961,0.00005739373,0.000009587357,0.00003563382,0.0004479667,0.0000308415,0.003126699],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001657293,"threshold_uncertainty_score":0.006698787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01030497089821206,"score_gpt":0.2460777017133133,"score_spread":0.2357727308151012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}