{"id":"W2029660830","doi":"10.1016/s0014-5793(03)00424-1","title":"PAK interacts with NCK and MLK2 to regulate the activation of jun N‐terminal kinase","year":2003,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"PAK1; Kinase; Chemistry; Cell biology; Signal transducing adaptor protein; c-jun; Adapter (computing); MAP kinase kinase kinase; GTPase; Signal transduction; Protein kinase A; Biology; Biochemistry; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001136592,0.00008703765,0.00007120843,0.0000312325,0.00005172799,0.00001697536,0.00005593277,0.00003419886,0.00001247546],"category_scores_gemma":[0.00004240033,0.00006064841,0.00002380384,0.00006934305,0.00005417561,0.000005051398,0.00002323105,0.00004370198,0.000001426239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006758799,"about_ca_system_score_gemma":0.00001641291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001123791,"about_ca_topic_score_gemma":0.000007169903,"domain_scores_codex":[0.9994829,0.00005385263,0.0001039063,0.0001620318,0.00008565967,0.000111681],"domain_scores_gemma":[0.9996639,0.000009054546,0.00006438272,0.0001847621,0.00003264379,0.00004524257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001063725,0.00001134179,0.0003758805,0.00001383849,0.00001693329,0.000003345042,0.00008813724,0.0002505842,0.9968113,0.0001318908,0.0006429704,0.001547382],"study_design_scores_gemma":[0.0003299886,0.0001208634,0.004874954,0.00005566251,0.00000986245,0.00002308074,0.00004131632,0.00002135517,0.9814928,0.00001665485,0.01291275,0.0001007212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993194,0.00005344239,0.004378035,0.002003863,0.00002470102,0.0001739932,0.000002206965,0.000004213975,0.0001655295],"genre_scores_gemma":[0.9962317,0.000003540954,0.001011333,0.002575093,0.00004549609,0.00001226449,0.00001286526,0.000009945139,0.00009776644],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01531853,"threshold_uncertainty_score":0.2473171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007356042738991689,"score_gpt":0.2227695483688316,"score_spread":0.21541350562984,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}