{"id":"W2029756629","doi":"10.1074/jbc.m804866200","title":"Distinct Contributions of the Lectin and Arm Domains of Calnexin to Its Molecular Chaperone Function","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Calnexin; Chaperone (clinical); Lectin; Cell biology; Biology; Chemistry; Computational biology; Endoplasmic reticulum; Calreticulin; Biochemistry; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001183277,0.0002212516,0.0001692301,0.00007837359,0.00007504426,0.0002859034,0.0001754962,0.0001808356,0.0006341264],"category_scores_gemma":[0.000184384,0.00009550676,0.000145106,0.00008083086,0.0002691993,0.0002809611,0.0001874064,0.0004232198,0.0001193641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003544271,"about_ca_system_score_gemma":0.0002211548,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005923519,"about_ca_topic_score_gemma":0.0009069131,"domain_scores_codex":[0.9999163,0.00001196389,0.000006517741,0.0000151466,0.00002974007,0.00002027988],"domain_scores_gemma":[0.9999092,0.00002053194,0.0000146823,0.000008248337,0.00001612041,0.0000313058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000673286,0.000008760206,0.0002528468,0.00001196761,0.000001775961,0.00003169823,0.000006088799,0.00006771027,0.9988042,0.00009936063,0.000007022087,0.000641252],"study_design_scores_gemma":[0.00003198858,0.0004140752,0.03841583,0.000008933773,0.00002026409,0.0008411426,0.00006767142,0.003773876,0.953928,0.0002541394,0.002234147,0.00000995244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977063,0.0008866638,0.0007513906,0.00004472195,0.000005077876,0.000005118771,0.00003937964,0.000006352874,0.0005549685],"genre_scores_gemma":[0.9970825,0.0005912348,0.001149539,0.00005518529,0.000006606273,0.00000762993,0.0001992645,0.000003588649,0.0009043058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006341264,"threshold_uncertainty_score":0.002571523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01399811547049851,"score_gpt":0.2421560599790344,"score_spread":0.2281579445085359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}