{"id":"W2029761239","doi":"10.1021/bi101558v","title":"Enzymatic Adenylation of 2,3-Dihydroxybenzoate Is Enhanced by a Protein−Protein Interaction between <i>Escherichia coli</i> 2,3-Dihydro-2,3-dihydroxybenzoate Dehydrogenase (EntA) and 2,3-Dihydroxybenzoate-AMP Ligase (EntE)","year":2010,"lang":"en","type":"article","venue":"Biochemistry","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"","keywords":"Enterobactin; Adenylylation; Tetramer; Chemistry; Dimer; Escherichia coli; Stereochemistry; Fumarase; Formate dehydrogenase; Enzyme; Biochemistry; Cofactor; Biosynthesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000822546,0.000957066,0.0009988903,0.0002152453,0.0004372781,0.0002736797,0.0006461066,0.0008516946,0.001210779],"category_scores_gemma":[0.0003376902,0.0009635716,0.0002964597,0.00062491,0.000508284,0.0008044491,0.0002940219,0.001007918,0.000182875],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001512844,"about_ca_system_score_gemma":0.0002057407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003167943,"about_ca_topic_score_gemma":0.00009250602,"domain_scores_codex":[0.9947519,0.0001742136,0.0015416,0.001553021,0.0009847002,0.000994566],"domain_scores_gemma":[0.9964929,0.0001384043,0.001253484,0.001196883,0.0003146816,0.0006036658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002103642,0.0001878546,0.0002457229,0.0005166808,0.00008425173,0.000004633383,0.000382667,0.000008707854,0.9960861,0.00003228562,0.001668227,0.0005725658],"study_design_scores_gemma":[0.00147288,0.0001617075,0.00009856716,0.0003682305,0.0001392417,0.00001730945,0.0001449802,0.0004951854,0.9933091,0.0004713839,0.002379862,0.0009415869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946128,0.000339527,0.001158283,0.0003146863,0.0005435039,0.00128738,0.00053457,0.0003321246,0.0008771699],"genre_scores_gemma":[0.9949891,0.00002591086,0.002029874,0.0002314008,0.0005140193,0.0002687078,0.0004169703,0.0001371494,0.001386894],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002776974,"threshold_uncertainty_score":0.9997023,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006953666695642122,"score_gpt":0.2297007347896695,"score_spread":0.2227470680940274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}