{"id":"W2029761239","doi":"10.1021/bi101558v","title":"Enzymatic Adenylation of 2,3-Dihydroxybenzoate Is Enhanced by a Protein−Protein Interaction between <i>Escherichia coli</i> 2,3-Dihydro-2,3-dihydroxybenzoate Dehydrogenase (EntA) and 2,3-Dihydroxybenzoate-AMP Ligase (EntE)","year":2010,"lang":"en","type":"article","venue":"Biochemistry","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"","keywords":"Enterobactin; Adenylylation; Tetramer; Chemistry; Dimer; Escherichia coli; Stereochemistry; Fumarase; Formate dehydrogenase; Enzyme; Biochemistry; Cofactor; Biosynthesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002924379,0.0005356434,0.0004166742,0.0001475272,0.0001576828,0.0004863187,0.0004135015,0.0002828241,0.001081881],"category_scores_gemma":[0.0001930867,0.0002843254,0.0003697165,0.0001833435,0.0003044516,0.0002146645,0.000355314,0.000694155,0.0005974618],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007113459,"about_ca_system_score_gemma":0.0002644576,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001137052,"about_ca_topic_score_gemma":0.001595064,"domain_scores_codex":[0.9996607,0.00008548031,0.0000274823,0.00008687595,0.00006758702,0.00007178851],"domain_scores_gemma":[0.9998264,0.00004384929,0.00004135792,0.00002278532,0.00001647083,0.00004926179],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004426865,0.0000220772,0.00008412419,0.00001566102,0.000004290274,0.00001268941,0.000007313616,0.00001985048,0.9994418,0.00004889482,0.00001899823,0.0002799685],"study_design_scores_gemma":[0.000006249308,0.00005021386,0.0008046245,0.000001744084,0.000003494509,0.00005560506,0.000005997934,0.0005290257,0.9976835,0.00001093835,0.0008453169,0.000003288384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914888,0.0007632976,0.005933416,0.0001010645,0.00003453156,0.00003556182,0.0002108161,0.0001320347,0.001300458],"genre_scores_gemma":[0.9918448,0.0003700949,0.00473535,0.00004669005,0.00001106019,0.0000216866,0.0005976437,0.00004253034,0.002330068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001137052,"threshold_uncertainty_score":0.005161226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006953666695642122,"score_gpt":0.2297007347896695,"score_spread":0.2227470680940274,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}