{"id":"W2029821989","doi":"10.1038/cr.2012.41","title":"Misfolded Gβ is recruited to cytoplasmic dynein by Nudel for efficient clearance","year":2012,"lang":"en","type":"article","venue":"Cell Research","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Science and Technology Commission of Shanghai Municipality; Institute of Molecular and Cell Biology; National Natural Science Foundation of China; Carnegie Institution of Washington; Chinese Academy of Sciences; University of Alberta; Thomas Jefferson University","keywords":"Aggresome; Dynein; Cell biology; MG132; Dynactin; Biology; Proteasome; Ubiquitin; Microtubule; Proteostasis; Endosome; Diaphorina citri; Cytoplasm; Biochemistry; Proteasome inhibitor; Gene; Intracellular","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002657249,0.0002410128,0.0002216954,0.0001744274,0.0002292712,0.000572387,0.0002867636,0.0003581161,0.0009887598],"category_scores_gemma":[0.0002059893,0.0002004931,0.000243018,0.00007542436,0.0002965497,0.0003029688,0.0004162276,0.0005843398,0.0005826572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006619481,"about_ca_system_score_gemma":0.0002668697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005323757,"about_ca_topic_score_gemma":0.0007920314,"domain_scores_codex":[0.9998677,0.00001780227,0.00001563091,0.00003003515,0.00003092144,0.00003801836],"domain_scores_gemma":[0.9998409,0.00001514745,0.00004194985,0.00002415584,0.00001390023,0.00006391576],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000761329,0.00001084748,0.0001138764,0.00001491644,0.000002682701,0.00007396873,0.000009614729,0.00006050697,0.9988956,0.0001660227,0.00006180978,0.0005139383],"study_design_scores_gemma":[0.00002064095,0.00005021568,0.001061752,0.000003520644,0.000003974439,0.0002926571,0.00001389618,0.001756602,0.9945363,0.00006052092,0.002195298,0.000004710262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946078,0.0007714893,0.003100948,0.0002002338,0.00004337811,0.00002537271,0.0001540396,0.0001341555,0.0009624654],"genre_scores_gemma":[0.9968085,0.0001514548,0.001365121,0.00005059177,0.00000601645,0.00001004884,0.0001530832,0.00002687616,0.001428272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009887598,"threshold_uncertainty_score":0.004802823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04506071216912395,"score_gpt":0.3597371334046002,"score_spread":0.3146764212354763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}