{"id":"W2029821989","doi":"10.1038/cr.2012.41","title":"Misfolded Gβ is recruited to cytoplasmic dynein by Nudel for efficient clearance","year":2012,"lang":"en","type":"article","venue":"Cell Research","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Science and Technology Commission of Shanghai Municipality; Institute of Molecular and Cell Biology; National Natural Science Foundation of China; Carnegie Institution of Washington; Chinese Academy of Sciences; University of Alberta; Thomas Jefferson University","keywords":"Aggresome; Dynein; Cell biology; MG132; Dynactin; Biology; Proteasome; Ubiquitin; Microtubule; Proteostasis; Endosome; Diaphorina citri; Cytoplasm; Biochemistry; Proteasome inhibitor; Gene; Intracellular","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007234078,0.0001304978,0.0001235388,0.00007827728,0.0001598992,0.00003432954,0.0003166309,0.0001795435,0.00004967525],"category_scores_gemma":[0.00008982929,0.0001285443,0.00008752433,0.000194481,0.00006205621,0.000002454013,0.0001697683,0.0001585307,0.0002023207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004532063,"about_ca_system_score_gemma":0.00007191126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002303416,"about_ca_topic_score_gemma":0.000006654838,"domain_scores_codex":[0.9983544,0.00008224326,0.0001630435,0.0003762303,0.0002320874,0.0007920082],"domain_scores_gemma":[0.9990158,0.00004192065,0.00002605473,0.0004404685,0.0002061969,0.0002695264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001636537,0.0001511594,0.0001710544,0.00003763699,0.00001005668,2.281056e-7,0.0001421129,0.00001929187,0.8169473,0.00001824994,0.18021,0.002129189],"study_design_scores_gemma":[0.0003257146,0.0001663213,0.0000703176,0.000008259824,0.000003159376,0.000001073864,0.00007337831,0.0003287457,0.613475,0.000004538803,0.3854323,0.0001111928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906582,0.002135816,0.003715426,0.0003686882,0.0001309914,0.000803238,0.0001057132,0.00001008876,0.002071785],"genre_scores_gemma":[0.9807065,0.0003362201,0.0008550457,0.000604799,0.0002257353,0.0001645404,0.0001476919,0.00004220993,0.01691733],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2052222,"threshold_uncertainty_score":0.5241882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04506071216912395,"score_gpt":0.3597371334046002,"score_spread":0.3146764212354763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}