{"id":"W2029828909","doi":"10.1038/cdd.2012.168","title":"Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model","year":2013,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; University of Toronto; Ontario Institute for Cancer Research; McGill University Health Centre","funders":"Universität Zürich; Oncosuisse","keywords":"Biology; Carcinogenesis; Cancer research; Gene knockdown; Downregulation and upregulation; Mitochondrion; Cell biology; Apoptosis; Carnitine; Gene; Endocrinology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001381929,0.0005442949,0.0003114877,0.0004923959,0.0003423791,0.0003479152,0.0004220116,0.0005036552,0.001348805],"category_scores_gemma":[0.0001666881,0.0002459358,0.0002819109,0.0002735521,0.0006011717,0.0002674856,0.0001977442,0.0009832269,0.0003325507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001152089,"about_ca_system_score_gemma":0.0006879735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004077485,"about_ca_topic_score_gemma":0.008099421,"domain_scores_codex":[0.9998417,0.00001906797,0.00001375288,0.00003404743,0.00004154831,0.00004983858],"domain_scores_gemma":[0.9997634,0.00003844108,0.00006516046,0.0000276165,0.00001817661,0.00008710332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000462785,0.00005031019,0.0001086405,0.00001449868,0.000005230318,0.00005674368,0.00001077409,0.0001439942,0.9980773,0.0002010944,0.00009844051,0.0007701315],"study_design_scores_gemma":[0.00002849337,0.0002583326,0.0008655386,0.000003024731,0.00001334168,0.000109616,0.00002087452,0.001167028,0.9964504,0.00007234963,0.001005857,0.000005140919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949321,0.0007682668,0.002141222,0.000345775,0.00008599422,0.00002028934,0.0005895811,0.0001821434,0.0009345982],"genre_scores_gemma":[0.9942814,0.000493268,0.001724232,0.00005248065,0.000008364965,0.00003810391,0.0003636735,0.00004837161,0.002990128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004077485,"threshold_uncertainty_score":0.008359015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008870766260750916,"score_gpt":0.1947702669613712,"score_spread":0.1858995007006203,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}