{"id":"W2029915978","doi":"10.1210/me.2007-0512","title":"Estrogen Regulates Snail and Slug in the Down-Regulation of E-Cadherin and Induces Metastatic Potential of Ovarian Cancer Cells through Estrogen Receptor α","year":2008,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":200,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; Estrogen receptor; Epithelial–mesenchymal transition; Cancer research; Slug; Carcinogenesis; Estrogen; Estrogen receptor alpha; Small interfering RNA; Metastasis; Transcription factor; Cell biology; Internal medicine; Endocrinology; Transfection; Cell culture; Cancer; Gene; Breast cancer; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007903382,0.0001534076,0.0001296795,0.0001515119,0.0001116383,0.0001665273,0.00005450407,0.00008539991,0.0007693248],"category_scores_gemma":[0.00006688112,0.00009983088,0.0001889941,0.00009558001,0.0001173592,0.00009930526,0.0001309401,0.0001916348,0.0001806248],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001202587,"about_ca_system_score_gemma":0.0001672458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006251741,"about_ca_topic_score_gemma":0.001280623,"domain_scores_codex":[0.9999487,0.000009521881,0.000005195405,0.000006566349,0.00001385186,0.00001614058],"domain_scores_gemma":[0.9999708,0.000003522096,0.000007781346,0.00000256866,0.000005442241,0.000009894895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001000839,0.00001671828,0.0006268317,0.00002561059,0.000003074064,0.00007207013,0.00001648737,0.00002730842,0.9980437,0.00007769672,0.00002815726,0.0009622511],"study_design_scores_gemma":[0.00003401667,0.0003052579,0.03952248,0.000008243568,0.00002105376,0.0004113269,0.00007642723,0.001365986,0.9536502,0.00009592487,0.004503537,0.000005491856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957749,0.001960382,0.0007348985,0.00006925696,0.0000113177,0.00001195521,0.0001238742,0.00002888681,0.001284673],"genre_scores_gemma":[0.9955043,0.001201577,0.0004847341,0.00004609039,0.000003791066,0.00001984591,0.0001919159,0.000005904906,0.002541811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007693248,"threshold_uncertainty_score":0.002573609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02248886066340055,"score_gpt":0.2713976503386747,"score_spread":0.2489087896752742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}