{"id":"W2029915978","doi":"10.1210/me.2007-0512","title":"Estrogen Regulates Snail and Slug in the Down-Regulation of E-Cadherin and Induces Metastatic Potential of Ovarian Cancer Cells through Estrogen Receptor α","year":2008,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":200,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biology; Estrogen receptor; Epithelial–mesenchymal transition; Cancer research; Slug; Carcinogenesis; Estrogen; Estrogen receptor alpha; Small interfering RNA; Metastasis; Transcription factor; Cell biology; Internal medicine; Endocrinology; Transfection; Cell culture; Cancer; Gene; Breast cancer; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008586951,0.0001506785,0.000420192,0.00009798826,0.00003556181,0.000004223735,0.0000811041,0.00005566636,0.00009424014],"category_scores_gemma":[0.00001924347,0.0001155278,0.00007190601,0.0001874084,0.0003312365,0.0000490103,0.00005386095,0.0001268857,9.602642e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001964295,"about_ca_system_score_gemma":0.00008337796,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001728145,"about_ca_topic_score_gemma":0.000031392,"domain_scores_codex":[0.9988426,0.0001354041,0.0003385889,0.0002556835,0.0001808669,0.0002468453],"domain_scores_gemma":[0.9994699,0.00003687252,0.0001547699,0.0002390024,0.0000579801,0.00004152536],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001840813,0.00009376597,0.002107021,0.0001117913,0.0001903855,0.0001021584,0.0009114685,0.00008118894,0.9880612,0.001933523,0.0000575001,0.006165867],"study_design_scores_gemma":[0.002055889,0.0002874887,0.02205507,0.00003855986,0.000274951,0.0004351133,0.000352227,0.000025559,0.9724485,0.0003948596,0.001524308,0.000107473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905979,0.007830872,0.0001999243,0.0007714041,0.00007649222,0.000372239,0.0000258973,0.000007707673,0.0001175845],"genre_scores_gemma":[0.9935043,0.0021283,0.004111288,0.00013117,0.00002535436,0.0000347946,0.0000159586,0.00001574548,0.00003309037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01994804,"threshold_uncertainty_score":0.4711085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02248886066340055,"score_gpt":0.2713976503386747,"score_spread":0.2489087896752742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}