{"id":"W2029971847","doi":"10.1002/cmdc.201000060","title":"Synthesis and Antitumor Activity of Ether Glycerophospholipids Bearing a Carbamate Moiety at the <i>sn</i>‐2 Position: Selective Sensitivity Against Prostate Cancer Cell Lines","year":2010,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Organophosphorus compounds synthesis","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"DU145; Chemistry; Moiety; Cell culture; Stereochemistry; Prostate cancer; Cancer cell; Apoptosis; In vivo; Ether; Programmed cell death; Biological activity; Carbamate; Cancer; Cancer research; Biochemistry; In vitro; Biology; LNCaP; Medicine; Internal medicine; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009728215,0.0004076709,0.0002114462,0.0002007157,0.00008741276,0.0001728947,0.0002389569,0.0002411638,0.000716851],"category_scores_gemma":[0.00008775963,0.000108701,0.0001814084,0.0001460169,0.0001260823,0.0001495515,0.0001451943,0.0003347439,0.0001895079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001918862,"about_ca_system_score_gemma":0.0001865668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005745025,"about_ca_topic_score_gemma":0.0009470612,"domain_scores_codex":[0.9999312,0.00001373675,0.000008212679,0.00001144879,0.00001697047,0.00001843827],"domain_scores_gemma":[0.9999316,0.000008362722,0.00002039765,0.000006987369,0.00001237596,0.0000203311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002070623,0.0000502783,0.0001057107,0.00006284075,0.000005913656,0.00006793978,0.0000130825,0.000246892,0.9956179,0.00008837423,0.00003332971,0.003500603],"study_design_scores_gemma":[0.00007366426,0.001789292,0.001303337,0.000005490929,0.00002540923,0.0002102731,0.00001090766,0.0002928563,0.9940653,0.00001692878,0.002200662,0.000005912677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927529,0.002628309,0.001659746,0.00005674278,0.00002198068,0.00008834434,0.0003496373,0.00005023848,0.002392098],"genre_scores_gemma":[0.9936547,0.002136805,0.002260589,0.00004197339,0.00001231905,0.00005941377,0.0005664144,0.00001067482,0.001257094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000716851,"threshold_uncertainty_score":0.002398133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006429959748770298,"score_gpt":0.2130386759544739,"score_spread":0.2066087162057036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}