{"id":"W2029971847","doi":"10.1002/cmdc.201000060","title":"Synthesis and Antitumor Activity of Ether Glycerophospholipids Bearing a Carbamate Moiety at the <i>sn</i>‐2 Position: Selective Sensitivity Against Prostate Cancer Cell Lines","year":2010,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Organophosphorus compounds synthesis","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"DU145; Chemistry; Moiety; Cell culture; Stereochemistry; Prostate cancer; Cancer cell; Apoptosis; In vivo; Ether; Programmed cell death; Biological activity; Carbamate; Cancer; Cancer research; Biochemistry; In vitro; Biology; LNCaP; Medicine; Internal medicine; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000448987,0.0004644872,0.0005685422,0.00002747011,0.0003637249,0.00006969955,0.0002444049,0.0002969511,0.0003605609],"category_scores_gemma":[0.0002136269,0.0003811063,0.0001814972,0.0002407308,0.0005387372,0.0002058082,0.0004016915,0.0006229332,0.00001203647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002917536,"about_ca_system_score_gemma":0.0001547483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001424855,"about_ca_topic_score_gemma":0.0008414554,"domain_scores_codex":[0.9979795,0.00006286863,0.000332626,0.000690698,0.0003881875,0.0005461579],"domain_scores_gemma":[0.9976864,0.0007837144,0.0003671885,0.0007640219,0.0002279202,0.000170706],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000243191,0.0001670112,0.01017122,0.000363964,0.0001254477,0.00001570543,0.0009972219,0.000008633558,0.9833703,0.000005279985,0.0002285033,0.004303491],"study_design_scores_gemma":[0.0003997906,0.000009966724,0.002332664,0.0001181936,0.0001415064,0.0000387252,0.0001896555,0.0003872479,0.9954672,0.00002571694,0.0004624817,0.0004267925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899015,0.0005200565,0.000003523547,0.0005818165,0.0001867572,0.0002161724,0.0002262721,0.0001292811,0.008234614],"genre_scores_gemma":[0.9977316,0.0004264477,0.0003183392,0.00009327287,0.0002480788,0.0001219496,0.000007548364,0.0001045427,0.0009481764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01209693,"threshold_uncertainty_score":0.9998641,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006429959748770298,"score_gpt":0.2130386759544739,"score_spread":0.2066087162057036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}