{"id":"W2029974064","doi":"10.1242/jcs.03444","title":"Src-dependent phosphorylation of β2-adaptin dissociates the β-arrestin–AP-2 complex","year":2007,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer; McGill University; Royal Victoria Hospital","funders":"","keywords":"Internalization; Phosphorylation; Endocytic cycle; Arrestin; Cell biology; Biology; Clathrin; G protein-coupled receptor; Proto-oncogene tyrosine-protein kinase Src; Endocytosis; Receptor; Signal transducing adaptor protein; Tyrosine; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009232001,0.0003459054,0.0001643513,0.0001490467,0.0001718448,0.0002632868,0.0001949202,0.0001505968,0.002315268],"category_scores_gemma":[0.0000958958,0.0001291105,0.0002808384,0.000141036,0.0001336449,0.0002034219,0.0002375469,0.0006078879,0.0008431005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003295791,"about_ca_system_score_gemma":0.0001812042,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005172069,"about_ca_topic_score_gemma":0.0007509044,"domain_scores_codex":[0.9999022,0.000008550637,0.000006528032,0.00002207994,0.00002922103,0.00003135601],"domain_scores_gemma":[0.9999475,0.000007529403,0.00001464307,0.000007007327,0.000007085561,0.00001623658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005988317,0.00002045239,0.0001740803,0.0000241391,0.000007002738,0.00007667323,0.00001389183,0.00003315807,0.9986296,0.0001517917,0.0000781719,0.000731191],"study_design_scores_gemma":[0.000028176,0.00006450294,0.02065719,0.000007323266,0.000009855227,0.0005961987,0.00003115285,0.002246875,0.9706923,0.00009981022,0.005559314,0.000007404391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937021,0.001159143,0.001853596,0.0001330034,0.0000448453,0.00002405479,0.000278664,0.00005769992,0.002746936],"genre_scores_gemma":[0.9897914,0.001061113,0.001346727,0.0001089339,0.00002192274,0.00004012175,0.001425494,0.00003322532,0.006170952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002315268,"threshold_uncertainty_score":0.007745385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01415445241508539,"score_gpt":0.2617934136154612,"score_spread":0.2476389612003758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}