{"id":"W2030050924","doi":"10.1111/j.1537-2995.2006.00986.x","title":"Randomized clinical trials in thrombotic thrombocytopenic purpura: where do we go from here?","year":2006,"lang":"en","type":"letter","venue":"Transfusion","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Thrombotic thrombocytopenic purpura; Von Willebrand factor; Platelet; Medicine; Fresh frozen plasma; Internal medicine; Pathophysiology; Randomized controlled trial; Apheresis; Immunology; Gastroenterology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02064098,0.001469522,0.01012323,0.001379324,0.0009210158,0.00431932,0.001863235,0.008450056,0.02026608],"category_scores_gemma":[0.05153313,0.0008297398,0.005309946,0.002638756,0.001753082,0.004957352,0.0009723452,0.007179098,0.001703982],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00255767,"about_ca_system_score_gemma":0.003303981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002120659,"about_ca_topic_score_gemma":0.003644001,"domain_scores_codex":[0.9725833,0.02222775,0.002396041,0.001200575,0.001084443,0.0005079057],"domain_scores_gemma":[0.9614429,0.02769378,0.00571528,0.001113789,0.002327497,0.001706743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.409532,0.002313507,0.002466804,0.158422,0.03461927,0.0002714321,0.000357972,0.001387144,0.0007049505,0.01243678,0.05760014,0.319888],"study_design_scores_gemma":[0.8279117,0.01482706,0.00307095,0.04946689,0.0194605,0.0001467124,0.0003896346,0.0009024621,0.0002201919,0.01228815,0.07117837,0.0001372478],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.02145917,0.8710102,0.002054973,0.06451268,0.02666615,0.004892356,0.001873584,0.0002441255,0.007286677],"genre_scores_gemma":[0.2917741,0.4742409,0.01300241,0.1655408,0.02509069,0.0195809,0.002734728,0.0002133317,0.007822142],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.02064098,"threshold_uncertainty_score":0.1091613,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08467105061637621,"score_gpt":0.3642555387414252,"score_spread":0.279584488125049,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}