{"id":"W2030051217","doi":"10.1139/v06-121","title":"Preparation of enantiopure long chain <i>threo</i>-2-amino-3-hydroxyesters via chiral morpholinone-derived azomethine ylids","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis and Catalytic Reactions","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Enantiopure drug; Cycloaddition; Aldehyde; Stereochemistry; Alkyl; Sphingosine; Azomethine ylide; Stereospecificity; Organic chemistry; 1,3-Dipolar cycloaddition; Medicinal chemistry; Enantioselective synthesis; Catalysis; Receptor; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000234026,0.0002294663,0.0004093621,0.0001020475,0.0001101659,0.00005487404,0.0003499344,0.0002486703,0.001144854],"category_scores_gemma":[0.000109522,0.0002265044,0.0002838456,0.0001747483,0.0001745679,0.0001941539,0.00001264027,0.0003654939,0.000005027831],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002463951,"about_ca_system_score_gemma":0.0007933886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002209517,"about_ca_topic_score_gemma":0.001239541,"domain_scores_codex":[0.9983225,0.00001245039,0.0007922016,0.0002048134,0.0003088162,0.0003591889],"domain_scores_gemma":[0.9982256,0.00005925111,0.0007085885,0.0003673583,0.0002255733,0.0004136568],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002800024,0.00005264367,0.004501542,0.000161938,0.00008852287,0.0001314901,0.000177291,0.0003437168,0.9924071,0.000008223449,0.001157752,0.0009417763],"study_design_scores_gemma":[0.0005710729,0.00001776622,0.002029372,0.0001896198,0.00009184529,0.0008727347,0.000183344,0.0001213331,0.9928721,0.0002077408,0.002605982,0.0002370692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807947,0.0006943192,0.0003632673,0.0002446506,0.000144605,0.00003869491,0.00005944288,0.00001168766,0.0176486],"genre_scores_gemma":[0.9959391,0.00001802326,0.0001602606,0.00003387099,0.0006611755,0.000003604085,0.00006330356,0.0000322939,0.003088315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01514442,"threshold_uncertainty_score":0.9997683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007261474315484353,"score_gpt":0.2237255116871325,"score_spread":0.2164640373716482,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}