{"id":"W2030059254","doi":"10.1002/cbic.200900633","title":"A Simple Calixarene Recognizes Post‐translationally Methylated Lysine","year":2009,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Michael Smith Health Research BC","keywords":"Histone; Methylation; Cationic polymerization; Lysine; Peptide; Chemistry; Computational biology; Posttranslational modification; Biochemistry; Residue (chemistry); Gene; Combinatorial chemistry; Biology; Amino acid; Enzyme; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001897053,0.0001948316,0.0001662968,0.00005080455,0.00008199652,0.00003086965,0.0001631911,0.0002193471,0.00008718474],"category_scores_gemma":[0.0001178923,0.0001969022,0.0001272411,0.0001692267,0.00003714686,0.000004628314,0.00002830038,0.0000837163,0.00002241794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001330497,"about_ca_system_score_gemma":0.00007357504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001209598,"about_ca_topic_score_gemma":0.00001101367,"domain_scores_codex":[0.9988677,0.00003425399,0.0002691235,0.0004011903,0.0001674603,0.0002602883],"domain_scores_gemma":[0.9991789,0.00001401416,0.00008627421,0.0003405943,0.0002641866,0.0001159635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006190427,0.00007339435,0.0003205938,0.000006108316,0.00003462505,0.000001986137,0.00003332242,0.00004218589,0.9881656,0.00004902593,0.000409627,0.01080165],"study_design_scores_gemma":[0.0005606104,0.000260324,0.006817947,0.000006307496,0.00002584068,0.00000291074,0.00001465894,0.00007770868,0.9790043,0.001563809,0.01140808,0.0002574894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886438,0.003043727,0.002890662,0.0006615844,0.00006764979,0.0001535778,0.00003341514,0.00003683087,0.00446874],"genre_scores_gemma":[0.9946398,0.0001970817,0.002161816,0.0005055613,0.0002639398,0.000007255038,0.001546103,0.00002223727,0.0006562727],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01099845,"threshold_uncertainty_score":0.8029439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009897451976221279,"score_gpt":0.2630298493589585,"score_spread":0.2531323973827372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}