{"id":"W2030059254","doi":"10.1002/cbic.200900633","title":"A Simple Calixarene Recognizes Post‐translationally Methylated Lysine","year":2009,"lang":"en","type":"article","venue":"ChemBioChem","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Michael Smith Health Research BC","keywords":"Histone; Methylation; Cationic polymerization; Lysine; Peptide; Chemistry; Computational biology; Posttranslational modification; Biochemistry; Residue (chemistry); Gene; Combinatorial chemistry; Biology; Amino acid; Enzyme; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002457888,0.0003705045,0.0002377617,0.0001297046,0.0001917077,0.0002126466,0.0005158337,0.0006257417,0.001234954],"category_scores_gemma":[0.0002851526,0.0001247269,0.0001725854,0.0001346184,0.0003202003,0.000246788,0.0002958739,0.0004384241,0.000514187],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002455244,"about_ca_system_score_gemma":0.0001655434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004779124,"about_ca_topic_score_gemma":0.0008090105,"domain_scores_codex":[0.9998173,0.0000272183,0.000007259759,0.00005266717,0.00005908633,0.00003649],"domain_scores_gemma":[0.9998253,0.00004621648,0.0000413352,0.00002441551,0.00002617055,0.00003652145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004569531,0.00001349648,0.00006822198,0.00003385498,0.000004264146,0.00002824101,0.00001125689,0.00007188765,0.9985764,0.0001293208,0.00003572717,0.0009815887],"study_design_scores_gemma":[0.0000244273,0.0005439786,0.000842361,0.000002620398,0.000007381504,0.0001912424,0.00001220269,0.0004668855,0.9956351,0.0000565942,0.002209086,0.00000816931],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863585,0.001085562,0.00803727,0.0001962208,0.00005841516,0.00007934225,0.0001094259,0.0001144776,0.003960785],"genre_scores_gemma":[0.9909621,0.0005932255,0.005013789,0.0001422888,0.00002675412,0.000039118,0.0001897726,0.00001016417,0.003022873],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001234954,"threshold_uncertainty_score":0.004131317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009897451976221279,"score_gpt":0.2630298493589585,"score_spread":0.2531323973827372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}