{"id":"W2030062212","doi":"10.1074/mcp.m700271-mcp200","title":"The Tale of Two Domains","year":2007,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":197,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chromatin immunoprecipitation; Histone methyltransferase; Methyltransferase; Histone methylation; Immunoprecipitation; Histone; Histone code; Histone H3; Chromatin; EZH2; Cell biology; Interactome; Chemistry; Methylation; Chromatin remodeling; Biology; Genetics; Gene; DNA methylation; Gene expression; Promoter; Nucleosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004024728,0.0007723877,0.0007891159,0.0007109623,0.001947977,0.003057225,0.001760838,0.001908475,0.03867225],"category_scores_gemma":[0.001299181,0.0006576048,0.0009057007,0.000712019,0.001391722,0.002577017,0.004244206,0.002194567,0.0247674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008047455,"about_ca_system_score_gemma":0.0009093103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009509596,"about_ca_topic_score_gemma":0.0005718095,"domain_scores_codex":[0.999516,0.00007504685,0.00002489632,0.0001376795,0.0001478306,0.00009845341],"domain_scores_gemma":[0.999608,0.00004513253,0.00004628515,0.00006731638,0.0000686687,0.0001647393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.000600907,0.0001970622,0.003489015,0.001813219,0.0004515598,0.005014646,0.003320927,0.002524998,0.2610595,0.2451267,0.1710625,0.305339],"study_design_scores_gemma":[0.00005959255,0.0001895266,0.002428213,0.0002219969,0.0001048727,0.002764515,0.0009525116,0.002405987,0.01825551,0.03119095,0.9413419,0.0000845192],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.2011413,0.04919384,0.2901312,0.02868284,0.01471361,0.000758834,0.004203021,0.02516773,0.3860076],"genre_scores_gemma":[0.5732247,0.01019575,0.08748429,0.01040818,0.001484545,0.0005317604,0.005425862,0.001510437,0.3097344],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.03867225,"threshold_uncertainty_score":0.1293715,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005479053044670571,"score_gpt":0.2469016209338737,"score_spread":0.2414225678892031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}