{"id":"W2030062212","doi":"10.1074/mcp.m700271-mcp200","title":"The Tale of Two Domains","year":2007,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":197,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chromatin immunoprecipitation; Histone methyltransferase; Methyltransferase; Histone methylation; Immunoprecipitation; Histone; Histone code; Histone H3; Chromatin; EZH2; Cell biology; Interactome; Chemistry; Methylation; Chromatin remodeling; Biology; Genetics; Gene; DNA methylation; Gene expression; Promoter; Nucleosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009229647,0.0001481687,0.0001188753,0.00003529717,0.0001349962,0.00002508487,0.000272351,0.0001257126,0.000003784598],"category_scores_gemma":[0.00009228262,0.0001233994,0.0001409086,0.0001168544,0.0001465824,0.000001962196,0.0001231453,0.0001018494,0.000005954058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001404583,"about_ca_system_score_gemma":0.00005511061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001912591,"about_ca_topic_score_gemma":0.00003335984,"domain_scores_codex":[0.9988276,0.0000704465,0.0003279124,0.0002581619,0.0002086378,0.0003071866],"domain_scores_gemma":[0.9990594,0.00001853284,0.0001602381,0.0005611824,0.0001224181,0.00007822293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004523012,0.00003251393,0.0006324586,0.000008220274,0.00003472329,0.000008393802,0.00002172444,0.000204745,0.9948546,0.001759597,0.00001522745,0.002382558],"study_design_scores_gemma":[0.0004447427,0.0001439609,0.0002445233,0.000004943405,0.00001665048,0.000002368522,0.00002469582,0.00008062553,0.9850251,0.00183497,0.01202987,0.0001475561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7754813,0.002658715,0.2196944,0.0000476285,0.0001068955,0.0003234729,0.00000410475,0.000006405547,0.001677041],"genre_scores_gemma":[0.989944,0.0001634307,0.009319373,0.00005045805,0.0001163807,0.00001420446,0.00005198891,0.00003427319,0.0003058678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2144627,"threshold_uncertainty_score":0.5032083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005479053044670571,"score_gpt":0.2469016209338737,"score_spread":0.2414225678892031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}