{"id":"W2030068760","doi":"10.1038/sj.onc.1206520","title":"TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-κB","year":2003,"lang":"en","type":"article","venue":"Oncogene","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":265,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Wilhelm Sander-Stiftung","keywords":"Apoptosis; Biology; FADD; Cancer research; XIAP; Cancer cell; Cell growth; Tumor necrosis factor alpha; Programmed cell death; Leukemia; Caspase 8; Cell culture; Cancer; Immunology; Caspase; Cell biology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002917741,0.0001811169,0.0001966358,0.00005125127,0.00006787956,0.00002799778,0.00006680267,0.0002845588,0.00004338954],"category_scores_gemma":[0.00003630103,0.0001680031,0.00004528536,0.0001406621,0.00001956994,0.000006498694,0.00001966015,0.00008356295,0.000001899662],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004379031,"about_ca_system_score_gemma":0.0001581402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001964424,"about_ca_topic_score_gemma":0.0007106956,"domain_scores_codex":[0.9988127,0.0001233131,0.0002572321,0.0003912324,0.0001715251,0.0002439747],"domain_scores_gemma":[0.999577,0.000007872372,0.00008206085,0.0001710653,0.00006167906,0.0001003128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001004018,0.00007474619,0.0001037222,0.00001535059,0.00002357628,0.000001087447,0.00008166903,0.00001107454,0.9926351,0.0000561849,0.0001929515,0.006704138],"study_design_scores_gemma":[0.00110204,0.0002817731,0.000660223,0.0000125538,0.00001914759,0.000001578982,0.00006778412,0.00007200213,0.9905849,0.00003291148,0.006943115,0.0002219682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976709,0.0006175437,0.000163529,0.0001898439,0.0002702694,0.0003041947,0.00004598628,0.00001066509,0.0007270857],"genre_scores_gemma":[0.998135,0.0007280493,0.0002399257,0.0001009173,0.00009735939,0.00006024374,0.0001923831,0.0000274628,0.0004186795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006750163,"threshold_uncertainty_score":0.6850966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02030547975549182,"score_gpt":0.2619280940972285,"score_spread":0.2416226143417367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}